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CLU

" in MedChemExpress (MCE) Product Catalog:

By Targets:	MAP3K (1) Small Interfering RNA (siRNA) (2)
By Research Areas:	Inflammation/Immunology (1) Neurological Disease (1)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

3

Inhibitors & Agonists

3

Recombinant Proteins

2

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

ASK1-IN-6	MAP3K	Neurological Disease Inflammation/Immunology
ASK1-IN-6 (Compound 32) is a selective inhibitor for apoptosis signal-regulating kinase 1 (ASK1), with an IC₅₀ of 25 nM. ASK1-IN-6 is blood brain barrier penetrate(rat Cl/Cl_u is 1.6/56 L/h/kg and K_p,uu is 0.46). ASK1-IN-6 exhibits anti-inflammatory avtivity and ameliorates the Alzheimer’s Disease in Tg4510 mouse model .

Clu Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)
Clu Mouse Pre-designed siRNA Set A contains three designed siRNAs for Clu gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Clu Mouse Pre-designed siRNA Set A Clu Mouse Pre-designed siRNA Set A

CLU Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CLU Human Pre-designed siRNA Set A contains three designed siRNAs for CLU gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CLU Human Pre-designed siRNA Set A CLU Human Pre-designed siRNA Set A

Species:	Human (2) Mouse (1)
Tag:	His (3) Fc (1)
Source:	HEK293 (3)

Cat. No.	Compare	Product Name	Species	Source

	Clusterin/APOJ Protein, Human (HEK293, Fc-His) rHuApolipoprotein J, C-Fc-His; ApoJ; CLUsterin; CLU; CLI; KUB1; Apolipoprotein J	Human	HEK293
	Clusterin/APOJ Protein, Human (HEK293, Fc-His) expresses in HEK293 with an Fc fragment and a His tag at the N-terminus. Apolipoprotein J (ApoJ) is involved in numerous physiological process important for lipid transportation, vascular smooth muscle cell differentiation, and has the potential for atherosclerosis.

	Clusterin/APOJ Protein, Human (HEK293, His) rHuCLUsterin/APOJ, His ; CLUsterin; Aging-Associated Gene 4 Protein; Apolipoprotein J; Apo-J; Complement Cytolysis Inhibitor; CLI; Complement-Associated Protein SP-40; Ku70-Binding Protein 1; NA1/NA2; Testosterone-Repressed Prostate Message 2; TRPM-2; CLU; APOJ; CLI; KUB1	Human	HEK293
	Clusterin/APOJ Protein, Human (HEK 293, His) expresses in HEK 293 cells with a His tag at the C-terminus. Clusterin (CLU) is a multifunctional glycoprotein that has been implicated in several physiological and pathological states, including Alzheimer’s disease (AD).

	Clusterin/APOJ Protein, Mouse (HEK293, His) rMuCLUsterin/CLU, His ; CLUsterin; Apolipoprotein J; CLUstrin; Sulfated glycoprotein 2	Mouse	HEK293
	Clusterin/APOJ proteins act as extracellular chaperones, inhibiting stress-induced plasma protein aggregation and preventing the formation of amyloid fibrils by various proteins. It maintains partially unfolded proteins in a proper state for refolding by other partners. Clusterin/APOJ Protein, Mouse (HEK293, His) is the recombinant mouse-derived Clusterin/APOJ protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Clusterin/APOJ Protein, Mouse (HEK293, His) is 427 a.a., with molecular weight of (29-43) & 67 kDa, respectively.

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