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CXCR4-IN-2

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-149558
    CXCR4-IN-2

    		Apoptosis CXCR Cancer
    CXCR4-IN-2 (compound A1) is a bifunctional fluorinated small molecule that is a potent CXCR4 inhibitor with anticancer activity. CXCR4-IN-2 has cytotoxic (IC50: 60 μg/mL; 72 h) and antiproliferative effects on mouse colorectal cancer (CRC) cells. CXCR4-IN-2 induces cell arrest in the G2/M phase and induces apoptosis .
    CXCR4-IN-2
  • HY-132936
    CXCR4 antagonist 2

    		CXCR Others
    CXCR4 antagonist 2 is a CXCR4 antagonist with an IC50 value of 47 nM.
    CXCR4 antagonist 2
  • HY-146054
    CXCR4 modulator-2

    		CXCR Inflammation/Immunology
    CXCR4 modulator-2 (compound Z7R) is a highly potent CXCR4 modulator with an IC50 value of 1.25 nM. CXCR4 modulator-2 has acceptable stability (t1/2 = 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model .
    CXCR4 modulator-2
  • HY-115493
    TIQ-15

    		CXCR Others
    TIQ-15 is a potent CXCR4 antagonist with an IC50 value of 6 nM for CXCR4 Ca 2+ flux. TIQ-15 inhibits CYP450 2D6 with an IC50 value of 0.32 μM .
    TIQ-15

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