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DBCO-PEG3-NHS ester

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By Targets:	ADC Linker (1)
By Research Areas:	Cancer (1)
Click Chemistry:	DBCO (1)

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Click Chemistry

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

DBCO-PEG3-NHS ester	ADC Linker	Cancer
DBCO-PEG3-NHS ester (cpmpd 45) is a ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

Cat. No.	Product Name		Classification

*Sulfo DBCO-PEG3-NHS* ester**		DBCO
Sulfo DBCO-PEG3-NHS ester is a click chemistry reagent containing an azide group. Sulfo DBCO-PEG3-NHS ester is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO group is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain and sulfo group increase water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only .

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