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DKK3

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

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Inhibitory Antibodies

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Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-RS03789

    Small Interfering RNA (siRNA) Others

    DKK3 Human Pre-designed siRNA Set A contains three designed siRNAs for DKK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    DKK3 Human Pre-designed siRNA Set A
    DKK3 Human Pre-designed siRNA Set A
  • HY-W107409

    Others Cancer
    Meridianin C is a marine natural product with anticancer activity. Meridianin C has significant inhibitory effects on four different human tongue cancer cells (YD-8, YD-10B, YD-38 and HSC-3). Meridianin C most strongly reduced the growth of YD-10B cells, the most aggressive and tumorigenic of the cell lines tested. Meridianin C also induced significant accumulation of large vesicles in YD-10B cells, validating its function through macrophagocytosis. Meridianin C reduces cellular levels of Dickkopf-related protein-3 (DKK-3), a known negative regulator of macrophagy. Meridianin C affects macrophagocytosis by downregulating DKK-3, thereby affecting cell proliferation .
    Meridianin C

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