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Results for "

DMT1

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Recombinant Proteins

2

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-126302
    DMT1 blocker 2
    2 Publications Verification

    		 Ferroportin Metabolic Disease
    DMT1 blocker 2 is a direct inhibitor of divalent metal transporter 1 (DMT1), with an IC50 of 0.83 μM. DMT1 blocker 2 can block iron uptake by enterocytes in vivo [1].
    DMT1 blocker 2
  • HY-126301
    DMT1 blocker 1
    2 Publications Verification

    		 Ferroportin Inflammation/Immunology
    DMT1 blocker 1 (compound 6f) is a blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM, is expected to block iron uptake by enterocytes in vivo [1].
    DMT1 blocker 1
  • HY-124703
    Pyrimidinone 8

    		Ferroportin Others
    Pyrimidinone 8 is a reversible linear non-competitive inhibitor of divalent metal transporter 1 (DMT1), with a Ki of 20 μM (hDMT1). Pyrimidinone 8 does not affect hDMT1 cell surface expression and shows no dependence with the extracellular pH. Pyrimidinone 8 can inhibit hDMT1-mediated iron uptake, with an IC50 of 13.8 μM [1].
    Pyrimidinone 8

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