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Results for "

DXR

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Peptides

1

Natural
Products

1

Recombinant Proteins

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162899
    DXR-IN-3

    		Others Infection
    DXR-IN-3 is a DXR inhibitor that specifically targets Toxoplasma gondii. DXR-IN-3 shows in vitro activity against the TgDXR enzyme, with an IC50 value of 0.62 μM and a Ki value of 0.19 μM. DXR-IN-3 can inhibit the proliferation of Toxoplasma, with an IC50 value of 5.46 μM .
    DXR-IN-3
  • HY-158335
    DXR-IN-1

    		Parasite Infection
    DXR-IN-1 (Compound 13E) is an inhibitor of 1-deoxy-D-ketose 5-phosphate reductoisomerase (DXR). DXR-IN-1 is highly selective for P. falciparum DXR (IC50=0.030 μM). DXR-IN-1 inhibits the growth of P. falciparum by binding to the active site of DXR and blocking its catalytic activity .
    DXR-IN-1
  • HY-121259
    Doxorubicinol

    Adriamycinol; DXR-OL

    		 Endogenous Metabolite Cardiovascular Disease
    Doxorubicinol, a potent inhibitor of the cardiac sarcoplasmic reticulum calcium pump, inhibits systolic myocardial function in isolated heart muscle. Doxorubicinol inhibits tumor cell growth and has cardiotoxicity.
    Doxorubicinol
  • HY-121259S
    Doxorubicinol-13C,d3 TFA

    Adriamycinol-13C,d3 TFA; DXR-OL-13C,d3 TFA

    		 Endogenous Metabolite Others
    Doxorubicinol- 13C,d3 (TFA) is the deuterium and 13C labeled Doxorubicinol TFA[1].
    Doxorubicinol-13C,d3 TFA
  • HY-162898
    Antibacterial agent 242

    		Bacterial Infection
    Antibacterial agent 242 is a potent 1-Deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) inhibitor against Toxoplasma gondii with an IC50 value of 5.46 μM. Antibacterial agent 242 inhibits the activity of TgDXR enzyme and the proliferation of T. gondii in vitro .
    Antibacterial agent 242
  • HY-149882
    Antimalarial agent 27

    		Parasite Infection
    Antimalarial agent 27 (compound 11a) is an antimalarial agent, potently targeting to P.falciparum (IC50=0.37 μM). Antimalarial agent 27 acts function via P.falciparum DXR (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibition (IC50=0.11 μM) .
    Antimalarial agent 27

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