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Dapagliflozin

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

4

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10450
    Dapagliflozin
    40+ Cited Publications

    BMS-512148

    		 SGLT Metabolic Disease Cancer
    Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin induces HIF1 expression and attenuates renal IR injury .
    Dapagliflozin
  • HY-128723
    Dapagliflozin impurity

    		SGLT Others
    Dapagliflozin impurity is an enantiomer of Dapagliflozin which is a sodium-glucose transporter 2 inhibitor .
    Dapagliflozin impurity
  • HY-10450S
    Dapagliflozin-d5

    BMS-512148-d5

    		 Isotope-Labeled Compounds SGLT Metabolic Disease Cancer
    Dapagliflozin-d5 is a deuterium labeled Dapagliflozin (HY-10450). Dapagliflozin is a competitive SGLT2 inhibitor .
    Dapagliflozin-d5
  • HY-125156
    Dapagliflozin-3-O-β-D-glucuronide

    BMS-801576

    		 Endogenous Metabolite Metabolic Disease
    Dapagliflozin-3-O-β-D-glucuronide (BMS-801576) is the metabolite of Dapagliflozin (HY-10450), and is formed in the liver and kidney by uridine diphosphate glucuronosyltransferase-1A9 (UGT1A9). Dapagliflozin is a selective inhibitor for SGLT2, that can be used to improve glycemic control and attenuate type 2 diabetes .
    Dapagliflozin-3-O-β-D-glucuronide
  • HY-400785
    Dapagliflozin impurity A

    		Drug Derivative Cancer
    Dapagliflozin impurity A (Compound A) is a dapagliflozin peroxide, a genotoxic impurity, can cause damage to human genetic material at very low concentrations, leading to genetic mutations and possibly tumorigenesis .
    Dapagliflozin impurity A
  • HY-10450R
    Dapagliflozin (Standard)

    		SGLT Metabolic Disease Cancer
    Dapagliflozin (Standard) is the analytical standard of Dapagliflozin. This product is intended for research and analytical applications. Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin induces HIF1 expression and attenuates renal IR injury .
    Dapagliflozin (Standard)
  • HY-10450S5
    Dapagliflozin-13C6-1

    		Isotope-Labeled Compounds SGLT Metabolic Disease Cancer
    Dapagliflozin- 13C6-1 is 13C labeled Dapagliflozin. Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin induces HIF1 expression and attenuates renal IR injury .
    Dapagliflozin-13C6-1
  • HY-10450AR
    Dapagliflozin ((2S)-1,2-propanediol, hydrate) (Standard)

    		SGLT Metabolic Disease Cancer
    Dapagliflozin ((2S)-1,2-propanediol, hydrate) (Standard) is the analytical standard of Dapagliflozin ((2S)-1,2-propanediol, hydrate). This product is intended for research and analytical applications. Dapagliflozin ((2S)-1,2-propanediol, hydrate) is the S-enantiomer of Dapagliflozin 1,2-propanediol, hydrate. Dapagliflozin ((2S)-1,2-propanediol, hydrate), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin ((2S)-1,2-propanediol, hydrate) induces HIF1 expression and attenuates renal IR injury .
    Dapagliflozin ((2S)-1,2-propanediol, hydrate) (Standard)
  • HY-10450S2
    Dapagliflozin-d4

    BMS-512148-d4

    		 Isotope-Labeled Compounds SGLT Metabolic Disease Cancer
    Dapagliflozin-d4 (BMS-512148-d4) is deuterium labeled Dapagliflozin. Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin induces HIF1 expression and attenuates renal IR injury .
    Dapagliflozin-d4
  • HY-10450S3
    Dapagliflozin-13C6

    BMS-512148-13C6

    		 Isotope-Labeled Compounds Metabolic Disease Cancer
    Dapagliflozin- 13C6 (BMS-512148- 13C6) is 13C labeled Dapagliflozin. Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin induces HIF1 expression and attenuates renal IR injury .
    Dapagliflozin-13C6
  • HY-10450A
    Dapagliflozin ((2S)-1,2-propanediol, hydrate)
    40+ Cited Publications

    BMS-512148 (2S)-1,2-propanediol, hydrate

    		 SGLT Metabolic Disease Cancer
    Dapagliflozin ((2S)-1,2-propanediol, hydrate) is the S-enantiomer of Dapagliflozin 1,2-propanediol, hydrate. Dapagliflozin ((2S)-1,2-propanediol, hydrate), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin ((2S)-1,2-propanediol, hydrate) induces HIF1 expression and attenuates renal IR injury .
    Dapagliflozin ((2S)-1,2-propanediol, hydrate)
  • HY-122473
    fluoro-Dapagliflozin

    		SGLT Metabolic Disease
    fluoro-Dapagliflozin, a structural analog of Dapagliflozin, is a selective SGLT2 inhibitor with Ki values of 5.3 nM and 330 nM for SGLT2 and SGLT1, respectively. fluoro-Dapagliflozin blocks glucose transport and glucose-coupled currents .
    fluoro-Dapagliflozin
  • HY-137145
    galacto-Dapagliflozin

    		SGLT Others
    Galacto-dapagliflozin is a selective inhibitor for hSGLT2 with Ki of 25 nM .
    galacto-Dapagliflozin

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