2. Membrane Transporter/Ion Channel
  3. SGLT
  4. Dapagliflozin-d5

Dapagliflozin-d5  (Synonyms: BMS-512148-d5)

Cat. No.: HY-10450S Purity: 98.01%
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Dapagliflozin-d5 is a deuterium labeled Dapagliflozin. Dapagliflozin is a competitive SGLT2 inhibitor[1].

For research use only. We do not sell to patients.

Dapagliflozin-d<sub>5</sub> Chemical Structure

Dapagliflozin-d5 Chemical Structure

CAS No. : 1204219-80-6

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1 mg USD 320 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Dapagliflozin-d5:

Dapagliflozin-d5 Related Antibodies

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Description

Dapagliflozin-d5 is a deuterium labeled Dapagliflozin. Dapagliflozin is a competitive SGLT2 inhibitor[1].

IC50 & Target

SGLT2

 

Molecular Weight

413.90

Formula

C21H20D5ClO6
CAS No.
Unlabeled CAS

461432-26-8
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@H](C2=CC(CC3=CC=C(C=C3)OC([2H])([2H])C([2H])([2H])[2H])=C(C=C2)Cl)O[C@@H]([C@H]([C@@H]1O)O)CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : ≥ 30 mg/mL (72.48 mM)

DMF : ≥ 30 mg/mL (72.48 mM)

Ethanol : ≥ 30 mg/mL (72.48 mM)

DMF : ≥ 30 mg/mL (72.48 mM)

DMSO : ≥ 30 mg/mL (72.48 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 30 mg/mL (72.48 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4160 mL 12.0802 mL 24.1604 mL
5 mM 0.4832 mL 2.4160 mL 4.8321 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / DMF / Ethanol / DMF / DMSO / DMSO 1 mM 2.4160 mL 12.0802 mL 24.1604 mL 60.4011 mL
5 mM 0.4832 mL 2.4160 mL 4.8321 mL 12.0802 mL
10 mM 0.2416 mL 1.2080 mL 2.4160 mL 6.0401 mL
15 mM 0.1611 mL 0.8053 mL 1.6107 mL 4.0267 mL
20 mM 0.1208 mL 0.6040 mL 1.2080 mL 3.0201 mL
25 mM 0.0966 mL 0.4832 mL 0.9664 mL 2.4160 mL
30 mM 0.0805 mL 0.4027 mL 0.8053 mL 2.0134 mL
40 mM 0.0604 mL 0.3020 mL 0.6040 mL 1.5100 mL
50 mM 0.0483 mL 0.2416 mL 0.4832 mL 1.2080 mL
60 mM 0.0403 mL 0.2013 mL 0.4027 mL 1.0067 mL
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Dapagliflozin-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dapagliflozin-d51204219-80-6BMS-512148-d5SGLTSodium-dependent glucose cotransporterscompetitivesodium/glucosecotransporter 2SGLT2Inhibitorinhibitorinhibit

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