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Results for "

EHMT1

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

2

Recombinant Proteins

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-111904
    EHMT2-IN-2

    		Histone Methyltransferase Cancer
    EHMT2-IN-2 is a potent EHMT inhibitor, with IC50s of all <100 nM for EHMT1 peptide, EHMT2 peptide and cellular EHMT2. Used in the research of blood disease or cancer [1].
    EHMT2-IN-2
  • HY-111778
    EHMT2-IN-1

    		Histone Methyltransferase Cancer
    EHMT2-IN-1 is a potent EHMT inhibitor, with IC50s of all <100 nM for EHMT1 peptide, EHMT2 peptide and cellular EHMT2. Used in the research of blood disorder or cancer [1].
    EHMT2-IN-1
  • HY-148817
    WDR5-0102

    		WDR5 Cancer
    WDR5-0102 is an inhibitor targeting WDR5-MLL1 interface (Kdis=7 μM, Kd=4 μM). WDR5-0102 suppresses MLL1 HMT activity, but not human H3K4 methyltransferase SETD7 and six other HMTs: G9a, EHMT1, SUV39H2, SETD8, PRMT3, and PRMT5 [1] .
    WDR5-0102
  • HY-15273
    UNC0638
    Maximum Cited Publications
    8 Publications Verification

    		 VSV Histone Methyltransferase Autophagy Influenza Virus Infection Cancer
    UNC0638 selectively inhibits G9a and GLP histone methyltransferases with IC50 of 15 nM and 19 nM, respectively. UNC0638 inhibits TNBC cell invasion and migration in vitro. UNC0638 is also an inhibitor of EHMT1/2 and induces fetal hemoglobin (HbF) expression in human erythroid progenitor cell culture. In addition, UNC0638 has anti-FMDV (foot-and-mouth disease virus) and anti-VSV (vesicular stomatitis virus) activities, with excellent potency and selectivity against multiple epigenetic and non-epigenetic targets [1] .
    UNC0638
  • HY-12583
    A-366
    3 Publications Verification

    		 Histone Methyltransferase Epigenetic Reader Domain Cancer
    A-366 is a potent, highly selective, peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP (EHMT1), respectively. A-366 shows >1000-fold selectivity over 21 other methyltransferases. A-366 is also a potent, nanomolar inhibitor of the Spindlin1-H3K4me3-interaction (IC50=182.6 nM). A-366 displays high affinity at human histamine H3 receptor (Ki=17 nM) and shows subtype selectivity among subsets of the histaminergic and dopaminergic receptor families [1] .
    A-366
  • HY-13808
    UNC 0631
    3 Publications Verification

    		 Histone Methyltransferase Cancer
    UNC 0631 is a potent histone methyltransferase G9a inhibitor with an IC50 of 4 nM. UNC 0631 potently reduces H3K9me2 levels in MDA-MB-231 cells with an IC50 of 25 nM [1].
    UNC 0631
  • HY-RS04227
    EHMT1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    EHMT1 Human Pre-designed siRNA Set A contains three designed siRNAs for EHMT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    EHMT1 Human Pre-designed siRNA Set A
    EHMT1 Human Pre-designed siRNA Set A
  • HY-RS04228
    Ehmt1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Ehmt1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ehmt1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ehmt1 Mouse Pre-designed siRNA Set A
    Ehmt1 Mouse Pre-designed siRNA Set A
  • HY-RS04229
    EHMT1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    EHMT1 Rat Pre-designed siRNA Set A contains three designed siRNAs for EHMT1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    EHMT1 Rat Pre-designed siRNA Set A
    EHMT1 Rat Pre-designed siRNA Set A
  • HY-110093
    UNC0638 hydrate

    		VSV Histone Methyltransferase Autophagy Influenza Virus Infection Cancer
    UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 of 15 nM and 19 nM, respectively. UNC0638 hydrate inhibits TNBC cell invasion and migration in vitro. UNC0638 hydrate is also an inhibitor of EHMT1/2 and induces fetal hemoglobin (HbF) expression in human erythroid progenitor cell culture. In addition, UNC0638 hydrate has anti-FMDV (foot-and-mouth disease virus) and anti-VSV (vesicular stomatitis virus) activities, with excellent potency and selectivity against multiple epigenetic and non-epigenetic targets [1] .
    UNC0638 hydrate
  • HY-13807
    UNC0646
    1 Publications Verification

    		 Histone Methyltransferase Cancer
    UNC0646 is a potent and selective histone methyltransferase G9a inhibitor with an IC50 of 6 nM. UNC0646 is also a potent GLP inhibitor (IC50 <15 nM) and highly selective for G9a/GLP over SETD7, SUV39H2, SETD8 and PRMT3. UNC0646 reduces H3K9me2 levels in MDA-MB-231 cells with an IC50 of 26 nM [1].
    UNC0646

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