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Results for "

EPR

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

6

Recombinant Proteins

1

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-136265
    BC-LI-0186

    		Aminoacyl-tRNA Synthetase Cancer
    BC-LI-0186 is a potent and selective inhibitor of Leucyl-tRNA synthetase (LRS; LeuRS) and Ras-related GTP-binding protein D (RagD) interaction (IC50=46.11 nM). BC-LI-0186 competitively binds to the RagD interacting site of LRS (Kd=42.1 nM) and has on effects on LRS-Vps34, LRS-EPRS, RagB-RagD association, mTORC1 complex formation or the activities of 12 kinases. BC-LI-0186 can effectively suppress the activity of cancer-associated?MTOR?mutants and the growth of rapamycin-resistant cancer cells.?BC-LI-0186 is a promising agent for lung cancer research .
    BC-LI-0186
  • HY-RS04451
    EPRS1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    EPRS1 Human Pre-designed siRNA Set A contains three designed siRNAs for EPRS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    EPRS1 Human Pre-designed siRNA Set A
    EPRS1 Human Pre-designed siRNA Set A
  • HY-147151
    AMCPy

    		Others Others
    AMCPy is a potent electron paramagnetic resonance (EPR) brain imaging agent, possessing excellent lipophilicity for blood−brain barrier (BBB) penetration .
    AMCPy
  • HY-W777072
    4-Isocyanato-TEMPO,Technical grade

    		HIV Others
    4-isocyanato TEMPO is a spin labeling reagent used to label the 2’-position in RNA. It has been used to study HIV-1 transactivation response RNA and hammerhead ribosome dynamics by electron paramagnetic resonance (EPR) spectroscopy.
    4-Isocyanato-TEMPO,Technical grade
  • HY-117925
    Personalised postprandial-targeting

    		HBV Others
    Personalised postprandial-targeting is a way to modulate water-heme interactions with activity against low-spin P450 complexes. Personalised postprandial-targeting is able to maintain the axial water ligands of CYP2C9 even in the presence of inhibitors. Personalised postprandial-targeting also allows the hydrogen atoms of the axial water ligands to be observed by EPR spectroscopy, providing insights into the enzyme active site .
    Personalised postprandial-targeting
  • HY-W131302
    Ethylenediaminediacetic acid

    N,N-Ethylenediglycine

    		 Others Cancer
    Ethylenediaminediacetic acid (N,N-Ethylenediglycine) is an important ligand that enhances the antiproliferative activity of metal complexes. The complexes formed by ethylenediacetic acid and metal ions exhibited significant antiproliferative properties in MCF-7 cancer cell line. The metal complexes of ethylenediacetic acid were able to interact with DNA and were studied by CD and EPR spectroscopy techniques. Ethylenediaminediacetic acid and its metal complexes were able to induce cell cycle arrest at the G(0)/G(1) phase. The crystal structure analysis of ethylenediacetic acid provided important structural information for understanding its biological activity .
    Ethylenediaminediacetic acid

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