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Pathways Recommended:	GPCR/G Protein

Results for "

Endo G

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Apoptosis (1) Arenavirus (1) Bcl-2 Family (1) Caspase (1) DNA/RNA Synthesis (1) Endogenous Metabolite (1) Phosphodiesterase (PDE) (1) PROTAC Linkers (2)
By Research Areas:	Cancer (4) Infection (2)
Click Chemistry:	ADC Synthesis (1) PROTAC Synthesis (2) BCN (2)

5

Inhibitors & Agonists

1

Antibodies

2

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

endo CNTinh-03	Phosphodiesterase (PDE)	Infection Cancer
Endo CNTinh-03 is inhibitor for the elevation of cAMP and cGMP induced by agonist, such as G protein-coupled receptors, adenylate cyclase, and guanylate cyclase (IC₅₀ is 4 μM). Endo CNTinh-03 inhibits cholera toxin- and Escherichia coli (STa) toxin- induced CFTR chloride current, ameliorates secretory diarrhea in mouse models, and prevents cyst growth in polycystic kidney disease model .

AVN-944 4 Publications Verification VX-944	Arenavirus DNA/RNA Synthesis Apoptosis Caspase Bcl-2 Family	Infection Cancer
AVN-944 (VX-944) is an orally active, potent, selective, noncompetitive and specific inhibitor of IMPDH (inosine monophosphate dehydrogenase). AVN-944 is an essential rate-limiting enzyme in de novo guanine nucleotide synthesis. AVN-944 is also an inhibitor of arenavirus RNA synthesis, and blocks arenavirus infection. AVN-944 has broad anti-cancer activities, and can be used for multiple myeloma (MM) and acute myeloid leukemia (AML) research .

Chimax-G Fungal Endo- and Exo- chitosanases	Endogenous Metabolite	Others
Chimax-G (Fungal Endo- and Exo- chitosanases) is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

*Boc-gly-PEG3-endo-BCN*	PROTAC Linkers ADC Linker	Cancer
Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-gly-PEG3-endo-BCN is also a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Boc-gly-PEG3-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

*Gly-PEG3-endo-BCN*	PROTAC Linkers	Cancer
Gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Gly-PEG3-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Cat. No.	Compare	Product Name	Application	Reactivity

	Endo G Antibody (YA1529) EndoG; EndonucleaseG; Mitochondrial Endonuclease G; NUCG_HUMAN	WB	Human, Mouse, Rat
	Endo G Antibody (YA1529) is a biotin-conjugated non-conjugated IgG antibody, targeting Endo G, with a predicted molecular weight of 33 kDa (observed band size: 30 kDa). Endo G Antibody (YA1529) can be used for WB experiment in human, mouse, rat background.

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Cat. No.	Product Name		Classification

*Boc-gly-PEG3-endo-BCN*		BCN PROTAC Synthesis ADC Synthesis
Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-gly-PEG3-endo-BCN is also a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Boc-gly-PEG3-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

*Gly-PEG3-endo-BCN*		BCN PROTAC Synthesis
Gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Gly-PEG3-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

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