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Fzd1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Small Interfering RNA (siRNA) (1) Wnt (1)
By Research Areas:	Cancer (1)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Vantictumab OMP-18R5	Wnt	Cancer
Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody. Vantictumab inhibits Wnt pathway signaling by binding to *FZD1/2/5/7/8* receptors. Vantictumab can be studied against cancers through direct actions on tumor cells, including CSCs, and effects on the stroma, such as metastatic HER2-negative breast cancer and metastatic pancreatic adenocarcinoma ^[1] .

FZD1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FZD1 Human Pre-designed siRNA Set A contains three designed siRNAs for FZD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FZD1 Human Pre-designed siRNA Set A FZD1 Human Pre-designed siRNA Set A

Cat. No.	Product Name	Target	Research Area

Vantictumab OMP-18R5	Wnt	Cancer
Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody. Vantictumab inhibits Wnt pathway signaling by binding to *FZD1/2/5/7/8* receptors. Vantictumab can be studied against cancers through direct actions on tumor cells, including CSCs, and effects on the stroma, such as metastatic HER2-negative breast cancer and metastatic pancreatic adenocarcinoma ^[1] .

Cat. No.	Product Name	Category	Target	Chemical Structure

Vantictumab OMP-18R5	Classification of Application Fields Disease Research Fields Cancer	Wnt
Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody. Vantictumab inhibits Wnt pathway signaling by binding to *FZD1/2/5/7/8* receptors. Vantictumab can be studied against cancers through direct actions on tumor cells, including CSCs, and effects on the stroma, such as metastatic HER2-negative breast cancer and metastatic pancreatic adenocarcinoma ^[1] .

Cat. No.	Compare	Product Name	Species	Source

	Frizzled-1 Protein, Mouse (HEK293, Fc) rMuFrizzled-1/Fz-1, Fc; Frizzled-1; Fz-1; mFz1; Fzd1; Frizzled homolog 1	Mouse	HEK293
	Frizzled-1 is a Wnt receptor that is primarily activated by WNT7B and to varying degrees by WNT3A, WNT3, WNT1, and WNT2, while resisting activation by other Wnt proteins. Its fundamental role in canonical Wnt/β-catenin signaling involves promiscuous activation, GSK-3 kinase inhibition, nuclear β-catenin accumulation, and Wnt target gene activation. Frizzled-1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Frizzled-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Frizzled-1 Protein, Mouse (HEK293, Fc) is 180 a.a., with molecular weight of 55-70 kDa.

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FZD1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
FZD1 Human Pre-designed siRNA Set A contains three designed siRNAs for FZD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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