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GAT 107

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-117611
    GAT107

    		nAChR Neurological Disease
    GAT107 (compound 1b) is a potent α7 nAChR ago-PAMs (positive allosteric modulators) .
    GAT107
  • HY-167922
    (R,R,S)-GAT107

    		Others Neurological Disease
    (R,R,S)-GAT107 is a fully agonistic positive modulator of α7 nicotinic receptors with significant biological activity. Its activity is entirely present in its (+)-isomer 1b, while (-)-isomer 1a does not affect its activity when used together. Studies have shown that (R,R,S)-GAT107 is the most potent ago-PAM for α7 nicotinic receptors currently known and has the potential for further in vivo evaluation .
    (R,R,S)-GAT107

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