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Glycerol metabolism

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) Biochemical Assay Reagents (2) Endogenous Metabolite (11) Fatty Acid Synthase (FASN) (1)
By Research Areas:	Infection (1) Inflammation/Immunology (1) Metabolic Disease (10) Neurological Disease (1)
Oligonucleotides:	Solvents (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Oligonucleotides

Targets Recommended: Mitochondrial Metabolism

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N8461

Reuterin 3-Hydroxypropionaldehyde; 3-Hydroxypropanal	Bacterial	Infection
Reuterin is a broad-spectrum antimicrobial agent active against Gram positive and Gram negative bacteria, as well as yeasts, moulds and protozoa. Reuterin is produced by specific strains of Lactobacillus reuteri during anaerobic metabolism of glycerol. Reuterin also demonstrates potent antimicrobial activity against a broad panel of human and poultry meat campylobacter spp. Isolates .

HY-P2733

Glycerol-3-phosphate oxidase, E. coli GPO	Endogenous Metabolite	Metabolic Disease
Glycerol-3-phosphate oxidase, E. coli (GPO) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase is the skeleton of phospholipids in membrane lipids, and also a substrate in the respiratory chain. Glycerol-3-phosphate oxidase produces electrons through oxidation .

HY-P2917

Glycerol kinase, microorganism GyK	Endogenous Metabolite	Others
Glycerol kinase (EC 2.7.1.30) (GyK) is a bacterial sugar kinase, is often used in biochemical studies. Glycerol kinase catalyzes the first step of glycerol metabolism by transforming the triol into glycerol-3-P (G3P). Glycerol kinase is crucial for regulating channel/facilitator-independent uptake of glycerol into the cell .

HY-P2917B

Glycerol kinase, Flavobacterium meningosepticum GyK, Flavobacterium meningosepticum	Endogenous Metabolite	Metabolic Disease
Glycerol kinase, Flavobacterium meningosepticum (GyK, Flavobacterium meningosepticum) is a thermostable glycerol kinase isolated from Flavobacterium meningosepticum. Glycerol kinase, Flavobacterium meningosepticum catalyzes the first step in glycerol metabolism by converting triol to glycerol-3-p (G3P). Glycerol kinase, Flavobacterium meningosepticum is essential for regulating glycerol uptake in cells that is independent of channels or facilitators and is useful for biochemical studies .

HY-P2725

Glycerol dehydrogenase	Endogenous Metabolite	Metabolic Disease
Glycerol dehydrogenase is a polyol dehydrogenase that catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone. Glycerol dehydrogenase can be used for glycerol metabolism in diverse microorganisms .

HY-P2733B

Glycerol 3-phosphate Oxidase, Aerococcus viridans GPO, Aerococcus viridans	Endogenous Metabolite	Metabolic Disease
Glycerol-3-phosphate oxidase, Aerococcus viridans (GPO, Aerococcus viridans) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase is the skeleton of phospholipids in membrane lipids, and also a substrate of respiratory chain. Glycerol-3-phosphate oxidase produces electrons through oxidation .

HY-P2733A

Glycerol 3-phosphate Oxidase, Pedio coccus sp. GPO, Pedio coccus sp.	Endogenous Metabolite	Metabolic Disease
Glycerol-3-phosphate oxidase, Pedio coccus sp. (GPO, Pedio coccus sp.) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase is the skeleton of phospholipids in membrane lipids, and also a substrate in the respiratory chain. Glycerol-3-phosphate oxidase produces electrons through oxidation .

HY-P2733C

Glycerol-3-phosphate oxidase, microorganism GPO, microorganism	Endogenous Metabolite	Metabolic Disease
Glycerol-3-phosphate oxidase, microorganism is an enzyme that catalyzes the oxidation of glycerol-3-phosphate to dihydroxyacetone phosphate, producing hydrogen peroxide in the process. Glycerol-3-phosphate oxidase is located in the mitochondria of microorganisms and is involved in the glycerol-3-phosphate cycle, regulating cellular energy metabolism. Glycerol-3-phosphate oxidase, microorganism can be used in conjunction with Lipoprotein Lipase and Glycerol Kinase to determine triglyceride levels .

HY-P2917A

Glycerol kinase, Cellulomonas sp. GyK, Cellulomonas sp.	Endogenous Metabolite	Others
Glycerol kinase, Cellulomonas sp. (EC 2.7.1.30) is a bacterial sugar kinase, is often used in biochemical studies. Glycerol kinase, Cellulomonas sp. catalyzes the first step of glycerol metabolism by transforming the triol into glycerol-3-P (G3P). Glycerol kinase, Cellulomonas sp. is crucial for regulating channel/facilitator-independent uptake of glycerol into the cell .

HY-E70417

Glycerol-3-phosphate dehydrogenase, Saccharomyces cerevisiae GPDH, Saccharomyces cerevisiae	Endogenous Metabolite	Others
Glycerol-3-phosphate dehydrogenase, Saccharomyces cerevisiae, is an enzyme involved in glycerol metabolism and energy production, responsible for catalyzing the oxidation of glycerol-3-phosphate (G3P) to dihydroxyacetone phosphate (DHAP). Glycerol-3-phosphate dehydrogenase, Saccharomyces cerevisiae, is the rate-limiting enzyme in glycerol production in Saccharomyces cerevisiae, and helps Saccharomyces cerevisiae adapt to high osmotic environments by regulating glycerol production and accumulation. Glycerol-3-phosphate dehydrogenase, Saccharomyces cerevisiae, can be used in research within the field of metabolic engineering .

HY-145537

1,3-Dipalmitoyl-2-eicosapentaenoyl glycerol	Endogenous Metabolite	Metabolic Disease
1,3-Dipalmitoyl-2-eicosapentaenoyl glycerol is a positional isomer of triglyceride that can affect lipid metabolism .

HY-149545

1,3-Palmitin-2-docosahexaenoin 1,3-Dipalmitoyl-2-docosahexaenoyl Glycerol	Fatty Acid Synthase (FASN)	Metabolic Disease
1,3-Palmitin-2-docosahexaenoin (1,3-Dipalmitoyl-2-docosahexaenoyl glycerol) is the isomer of triacylglycerol (TAG), in which docosahexaenoic acid (DHA) is located at the β position (sn-2) of the glycerol backbone. 1,3-Palmitin-2-docosahexaenoin inhibits fatty acid synthase and cholesterol metabolism enzymes, activates carnitine palmitoyltransferase (CPT) in liver mitochondria and promotes β-oxidation of fatty acids. 1,3-Palmitin-2-docosahexaenoin exhibits lipid metabolism regulating activity .

HY-114886

IGP-5	Others	Metabolic Disease
IGP-5 is a mitochondrial *sn-Glycerol* 3-phosphate Dehydrogenase (mGPDH) inhibitor with the IC₅₀** of 0.7 μM aganist mGPDH H2O2 production . IGP-5 can be used for study of energy metabolism .

HY-W127409

1,2-Dimyristoyl-rac-glycerol	Biochemical Assay Reagents	Others
1,2-Dimyristoyl-rac-glycerol (C14:0) is a carboxylic acid ester, glycerolipid and diglyceride with an additional myristoyl group that facilitates interactions between proteins and lipids. Can be used as detergent or reagent. It plays a role in cell biology experiments involving the metabolism and metabolic pathways of glycerolipids. As a diglyceride, this substance consists of two fatty acid chains covalently bonded in the 1,2-form to a glycerol molecule. The diglyceride (DAG) study investigated the process by which DAG is depleted to inhibit fat accumulation. Reagent grade, for research use only.

HY-158362A

Monoglyceride lipase, Bacillus sp.	Endogenous Metabolite	Neurological Disease Metabolic Disease Inflammation/Immunology
Monoglyceride lipase, Bacillus sp., is a key enzyme involved in lipid metabolism. It catalyzes the hydrolysis of monoglycerides (particularly 2-AG, or 2-arachidonoylglycerol) into glycerol and free fatty acids. By regulating the levels of 2-AG, Monoglyceride lipase, Bacillus sp., can influence neural signaling, pain perception, inflammatory responses, and metabolic processes .

HY-154487

Glycerol dioleate	Biochemical Assay Reagents	Others
Glycerol dioleate can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

Cat. No.	Product Name	Type

HY-W127409

1,2-Dimyristoyl-rac-glycerol	Drug Delivery
1,2-Dimyristoyl-rac-glycerol (C14:0) is a carboxylic acid ester, glycerolipid and diglyceride with an additional myristoyl group that facilitates interactions between proteins and lipids. Can be used as detergent or reagent. It plays a role in cell biology experiments involving the metabolism and metabolic pathways of glycerolipids. As a diglyceride, this substance consists of two fatty acid chains covalently bonded in the 1,2-form to a glycerol molecule. The diglyceride (DAG) study investigated the process by which DAG is depleted to inhibit fat accumulation. Reagent grade, for research use only.

1,2-Dimyristoyl-rac-glycerol

Drug Delivery

1,2-Dimyristoyl-rac-glycerol (C14:0) is a carboxylic acid ester, glycerolipid and diglyceride with an additional myristoyl group that facilitates interactions between proteins and lipids. Can be used as detergent or reagent. It plays a role in cell biology experiments involving the metabolism and metabolic pathways of glycerolipids. As a diglyceride, this substance consists of two fatty acid chains covalently bonded in the 1,2-form to a glycerol molecule. The diglyceride (DAG) study investigated the process by which DAG is depleted to inhibit fat accumulation. Reagent grade, for research use only.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8461

Reuterin 3-Hydroxypropionaldehyde; 3-Hydroxypropanal	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Bacterial
Reuterin is a broad-spectrum antimicrobial agent active against Gram positive and Gram negative bacteria, as well as yeasts, moulds and protozoa. Reuterin is produced by specific strains of Lactobacillus reuteri during anaerobic metabolism of glycerol. Reuterin also demonstrates potent antimicrobial activity against a broad panel of human and poultry meat campylobacter spp. Isolates .

Cat. No.	Product Name		Classification

HY-154487

Glycerol dioleate		Solvents
Glycerol dioleate can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

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