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Guanethidine

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0800
    Guanethidine sulfate
    1 Publications Verification

    Guanethidine monosulfate

    		 Adrenergic Receptor Cardiovascular Disease Neurological Disease
    Guanethidine sulfate (Guanethidine monosulfate), an antihypertensive agent, is an adrenergic neurone blocking agent. Guanethidine sulfate enters noradrenergic nerve terminals by the neuronal amine carrier .
    Guanethidine sulfate
  • HY-B1251
    Guanethidine

    		Adrenergic Receptor Cardiovascular Disease Neurological Disease
    Guanethidine sulphate was synthesized in 1959. Guanethidine is thought to lowing blood pressure by interfering with the metabolism of chemical transmitter substances in post-ganglionic sympathetic nerve fibres.
    Guanethidine
  • HY-B0800R
    Guanethidine (sulfate) (Standard)

    		Adrenergic Receptor Neurological Disease
    Guanethidine (sulfate) (Standard) is the analytical standard of Guanethidine (sulfate). This product is intended for research and analytical applications. Guanethidine sulfate (Guanethidine monosulfate), an antihypertensive agent, is an adrenergic neurone blocking agent. Guanethidine sulfate enters noradrenergic nerve terminals by the neuronal amine carrier .
    Guanethidine (sulfate) (Standard)
  • HY-108247
    Guanethidine sesquisulfate

    		Adrenergic Receptor Cardiovascular Disease Neurological Disease
    Guanethidine sesquisulfate, an antihypertensive agent, is an adrenergic neurone blocking agent. Guanethidine sesquisulfate enters noradrenergic nerve terminals by the neuronal amine carrier .
    Guanethidine sesquisulfate
  • HY-16094
    Bethanidine sulfate

    BW 467C60

    		 Adrenergic Receptor Neurological Disease
    Bethanidine sulfate and its ortho-chloro derivative (BW 392C60) are potent adrenergic neurone blockers with sympathomimetic effects similar to bretylium and guanethidine in various animal models, particularly in cats. They inhibit the release of noradrenaline during nerve stimulation and enhance smooth muscle responses to adrenaline and noradrenaline. Bethanidine sulfate increases pressor responses to tyramine, though this effect diminishes with higher doses. Unlike guanethidine, Bethanidine sulfate does not deplete pressor amine content in the iris of cats post-administration. It also briefly inhibits autonomic cholinergic mechanisms and causes temporary neuromuscular paralysis in large doses, contrasting with its prolonged adrenergic neurone blocking effects .
    Bethanidine sulfate

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