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Heat Shock Protein Inhibitor I

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100110
    KNK437
    2 Publications Verification

    Heat Shock Protein Inhibitor I

    HSP Cancer
    KNK437 is a HSP inhibitor, and inhibits the induction of HSP105, HSP70, and HSP40.
    KNK437
  • HY-N12887

    Mitochondrial Metabolism Others Cancer
    Mycothiazole is an inhibitor for mitochondrial electron transport chain (ETC) complex I. Mycothiazole exhibits cytotoxicity in cancer cells Huh7 (IC50 is 55.8 μM), U87 and MCF7. Mycothiazole induces apoptosis in Huh7. Mycothiazole utilizes the unfolded protein response (UPR) and heat shock response (HSR) pathway involved transcription factors ATFS-1 and HSF1, to extend the lifespan of C. elegans .
    Mycothiazole

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