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IDH1/2-IN-1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162772
    IDH1/2-IN-1

    		Isocitrate Dehydrogenase (IDH) Apoptosis Cancer
    IDH1/2-IN-1 (Compound 6b) serves as a dual inhibitor of IDH1(R132H)/IDH2(R140Q) with IC50 values of 0.22 μM and 1.6 μM, respectively. IDH1/2-IN-1 effectively inhibits tumor growth by suppressing tumor cell proliferation and enhancing host defense through the activation of antioxidant enzymes. Additionally, IDH1/2-IN-1 reduces inflammation and promotes apoptosis, demonstrating robust antitumor activity. IDH1/2-IN-1 holds potential for research in leukemia .
    IDH1/2-IN-1

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