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Results for "

IFB-088

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-111022
    Icerguastat

    Sephin1; IFB-088

    		 Phosphatase Infection Inflammation/Immunology
    Icerguastat (Sephin1), a derivative of Guanabenz lacking the α2-adrenergic activity, is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). Icerguastat inhibits eIF2α dephosphorylation, thereby prolonging the protective response. Anti-prion effect .
    Icerguastat
  • HY-18956
    (E/Z)-Icerguastat

    (E/Z)-Sephin1; (E/Z)-IFB-088

    		 Phosphatase Inflammation/Immunology
    (E/Z)-Icerguastat ((E/Z)-Sephin1) is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). (E/Z)-Icerguastat can be used for protein misfolding diseases research .
    (E/Z)-Icerguastat
  • HY-110365
    Icerguastat Carbonate

    Sephin1 Carbonate; IFB-088 Carbonate

    		 Phosphatase Infection
    Icerguastat (Sephin1) Carbonate, a derivative of Guanabenz lacking the α2-adrenergic activity, is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). Icerguastat Carbonate inhibits eIF2α dephosphorylation, thereby prolonging the protective response. Anti-prion effect .
    Icerguastat Carbonate
  • HY-18956B
    (E/Z)-Icerguastat acetate

    (E/Z)-Sephin1 acetate; (E/Z)-IFB-088 acetate

    		 Phosphatase Inflammation/Immunology
    (E/Z)-Icerguastat ((E/Z)-Sephin1) acetate is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). (E/Z)-Icerguastat acetate can be used for protein misfolding diseases research .
    (E/Z)-Icerguastat acetate
  • HY-18956A
    (E/Z)-Icerguastat hydrochloride

    (E/Z)-Sephin1 hydrochloride; (E/Z)-IFB-088 hydrochloride

    		 Phosphatase Neurological Disease
    (E/Z)-Icerguastat hydrochloride ((E/Z)-Sephin1 hydrochloride) is a selective inhibitor with activity that prolongs the phosphorylation effects of eIF2α. (E/Z)-Icerguastat hydrochloride protects cells from defects in proteostasis. (E/Z)-Icerguastat hydrochloride was shown to significantly extend the survival of infected prion mice in a mouse model. (E/Z)-Icerguastat hydrochloride effectively reduces PrPSc expression and prion sequence activity in various neuronal cell lines persistently infected with different prion strains .
    (E/Z)-Icerguastat hydrochloride

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