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Results for "

IMR-90

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-169265
    BRD-K20733377

    		Bcl-2 Family Others
    BRD-K20733377 is an inhibitor for Bcl-2, and exhibits selective cytotoxicity against senescent cells, that inhibits the viability of Etoposide (HY-13629)-induced IMR-90 senescent cell with an IC50 of 10.7 μM. BRD-K20733377 reduces the mRNA expression of aging-related genes p16, p21 and KI67 in aged mouse model .
    BRD-K20733377
  • HY-169267
    BRD-K44839765

    		Bcl-2 Family Metabolic Disease
    BRD-K44839765 is selective against Bcl-2 with an IC50 value of 5.6 μM in IMR-90 cell. BRD-K44839765 has oral activity .
    BRD-K44839765
  • HY-101368A
    WIN 64338 hydrochloride

    		Bradykinin Receptor mAChR Neurological Disease
    WIN 64338 hydrochloride is a potent, selective, nonpeptide competitive antagonist of bradykinin B2 receptor. WIN 64338 hydrochloride inhibits [ 3H]-Bradykinin binding to the bradykinin B2 receptor on human IMR-90 cells with a Ki of 64 nM. WIN 64338 hydrochloride also can inhibits [ 3H]Quinuclidinyl benzilate binding to the rat brain muscarinic receptor (Ki=350 nM) .
    WIN 64338 hydrochloride

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