Search Result

Results for "

IgG2κ

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (1) c-Fms (1) CCR (1) CD28 (2) CRAC Channel (1) CXCR (2) FGFR (1) GCGR (1) Insulin Receptor (1) Interleukin Related (8) MMP (1) Notch (1) TGF-beta/Smad (1) TNF Receptor (3) Transmembrane Glycoprotein (2) Trk Receptor (1)
By Research Areas:	Cancer (2) Inflammation/Immunology (27) Metabolic Disease (1) Neurological Disease (2)

Inhibitors & Agonists

Inhibitory Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990012

Vamikibart	Interleukin Related	Inflammation/Immunology
Vamikibart is a chimeric humanized IgG2κ antibody targeting IL6 .

HY-P99909

Elranatamab PF-06863135	TNF Receptor	Inflammation/Immunology
Elranatamab (PF-06863135) is an anti-CD3E/TNFRSF17 human IgG2κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990712

Ersodetug	Insulin Receptor	Inflammation/Immunology
Ersodetug is an anti-INSR (insulin receptor) human IgG2 κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P99729

Melrilimab GSK 3772847; CNTO-7160	Interleukin Related	Inflammation/Immunology
Melrilimab (GSK 3772847) is an IgG2-kappa *anti-IL1RL1/ST2/IL33R/DER4/FIT-1* monoclonal antibody. Melrilimab can be used for the research of asthma .

HY-P990011

Sabirnetug	Amyloid-β	Neurological Disease
Sabirnetug is a humanized IgG2κ antibody targeting the Amyloid-β A4 precursor protein.

HY-P990013

Gulgafafusp alfa Glutazumab; GMA-102; GMA-105	GCGR	Metabolic Disease
Gulgafafusp alfa is a human IgG2κ antibody targeting the glucagon-like peptide 1 receptor GLP1R .

HY-P990982

Denrakibart	CCR	Inflammation/Immunology
HY-P990982 is an CCL17-targeting IgG2κ type human antibody, the recommed isotype control is Human IgG2 kappa, Isotype Control (HY-P99002) .

HY-P990937

Pacibekitug	Interleukin Related	Inflammation/Immunology
HY-P990937 is an IL6-targeting IgG2κ type human antibody, the recommed isotype control is Human IgG2 kappa, Isotype Control (HY-P99002) .

HY-P99893

Rozibafusp alfa AMG-570	CD28 TNF Receptor	Others
Rozibafusp alfa (AMG-570) is a humanized IgG2-κ monoclonal antibody targets ICOSL and BAFF. Prezalumab demonstrates beneficial activities on the arthritis of systemic lupus erythematosus. Prezalumab can be used for the research of sjogren's syndrome cutaneous lupus erythematosus, psoriasis and systemic lupus erythematosus (SLE) ^[2].

HY-P990713

Nolavetbart	Interleukin Related	Inflammation/Immunology
Nolavetbart is an anti-Canlupfam IL31RA human IgG2 κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990699

Riltovetbart ZTS-00008183	Interleukin Related	Inflammation/Immunology
Riltovetbart is a canine-derived IgG2 κ monoclonal antibody raised against Canlupfam IL13 .

HY-P990587

FR104	CD28	Inflammation/Immunology
FR104 is a humanized antibody expressed in CHO cells that targets CD28. FR104 comprises a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for FR104 can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990662

Sapelizumab	Interleukin Related	Inflammation/Immunology
Sapelizumab is a CHO-expressed humanized antibody targeting IL-6Ra/CD126. Sapelizumab has a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Sapelizumab can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990467

Anti-MICB Antibody	Transmembrane Glycoprotein	Inflammation/Immunology
The Anti-MICB Antibody is a humanized antibody expressed in CHO cells, targeting MICB. The Anti-MICB Antibody contains a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 143.66 kDa. The isotype control for the Anti-MICB Antibody can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990460

Anti-LAP Antibody	TGF-beta/Smad	Inflammation/Immunology
Anti-LAP Antibody is a humanized antibody expressed in CHO cells, targeting LAP. The Anti-LAP Antibody features a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. For isotype control of the Anti-LAP Antibody, you can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P991048

AMG-820	c-Fms	Cancer
AMG-820 is a fully human IgG2 antibody that targets CSF-1R. AMG-820 inhibits binding of the ligands CSF1 and IL34 and subsequent ligand-induced receptor activation. The isotype control for AMG-820 can refer to Human IgG2 kappa, Isotype Control (HY-P99002) .

HY-P990638

NI-0701	CXCR	Inflammation/Immunology
NI-0701 is a humanized antibody expressed in CHO cells that targets CCL5/RANTES. NI-0701 has a huIgG2 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for NI-0701 can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990474

Anti-NGF/bNGF Antibody	Trk Receptor	Inflammation/Immunology
Anti-NGF/bNGF Antibody is a CHO-expressed humanized antibody that targets NGF/bNGF. Anti-NGF/bNGF Antibody has a huIgG2a heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.14 kDa. The isotype control for Anti-NGF/bNGF Antibody can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990597

HuGAL-F2	FGFR	Inflammation/Immunology
HuGAL-F2 is a human-derived antibody expressed in CHO cells, targeting *FGF2. HuGAL-F2 contains a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for HuGAL-F2 can refer to Human IgG2* kappa, Isotype Control (HY-P99002).

HY-P990476

Anti-NOTCH1 Antibody	Notch	Inflammation/Immunology
The Anti-NOTCH1 Antibody is a CHO-expressed human antibody targeting NOTCH1. The Anti-NOTCH1 Antibody has a huIgG2 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for the Anti-NOTCH1 Antibody can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990478

Anti-Orai1 Antibody	CRAC Channel	Inflammation/Immunology
Anti-Orai1 Antibody is a humanized antibody expressed in CHO cells that targets Orai1. The Anti-Orai1 Antibody has a huIgG2 heavy chain and a huλ light chain, with an predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-Orai1 Antibody can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990468

Anti-MMP9 Antibody	MMP	Inflammation/Immunology
Anti-MMP9 Antibody is a CHO-expressed human antibody that targets MMP9. The Anti-MMP9 Antibody is composed of a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.76 kDa. For the isotype control of the Anti-MMP9 Antibody, you can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990317

AGS-67E	Transmembrane Glycoprotein	Inflammation/Immunology
AGS-67E is a humanized antibody expressed by CHO, targeting TSPAN26/CD37. AGS-67E has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 143.44 kDa. The isotype control for AGS-67E can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990321

AMG-108 MEDI 8968	Interleukin Related	Inflammation/Immunology
AMG-108 is a humanized antibody expressed in CHO cells, targeting IL-1R1/CD121a. AMG-108 is composed of a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for AMG-108 can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990313

ABX-IL8	CXCR Interleukin Related	Inflammation/Immunology
ABX-IL8 is a human-derived antibody expressed in CHO cells, targeting CXCL8/IL-8. ABX-IL8 contains a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 143.94 kDa. The isotype control for ABX-IL8 can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990528

Anti-TNFRSF7/CD27 Antibody	TNF Receptor	Inflammation/Immunology
Anti-TNFRSF7/CD27 Antibody is a CHO-expressed human antibody targeting TNFRSF7/CD27. The Anti-TNFRSF7/CD27 Antibody contains huIgG2 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-TNFRSF7/CD27 Antibody can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

Cat. No.	Product Name	Target	Research Area

HY-P99002

*Human IgG2* kappa, Isotype Control**	Inhibitory Antibodies	Inflammation/Immunology
Human IgG2 kappa, Isotype Control, a human monoclonal antibody, is an isotype control for human IgG2κ antibody .

HY-P990012

Vamikibart	Interleukin Related	Inflammation/Immunology
Vamikibart is a chimeric humanized IgG2κ antibody targeting IL6 .

HY-P99677

Izenivetmab ZTS-00075623	Inhibitory Antibodies	Neurological Disease
Izenivetmab (ZTS-00075623) is a caninized IgG2κ anti-NGFB monoclonal antibody .

HY-P99909

Elranatamab PF-06863135	TNF Receptor	Inflammation/Immunology
Elranatamab (PF-06863135) is an anti-CD3E/TNFRSF17 human IgG2κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990011

Sabirnetug	Amyloid-β	Neurological Disease
Sabirnetug is a humanized IgG2κ antibody targeting the Amyloid-β A4 precursor protein.

HY-P990010

Devextinetug IXT-M200	Inhibitory Antibodies	Cancer
Devextinetug (IXT-M200) is a chimeric anti-methamphetamine, mouse-derived IgG2κ antibody .

HY-P990013

Gulgafafusp alfa Glutazumab; GMA-102; GMA-105	GCGR	Metabolic Disease
Gulgafafusp alfa is a human IgG2κ antibody targeting the glucagon-like peptide 1 receptor GLP1R .

HY-P990982

Denrakibart	CCR	Inflammation/Immunology
HY-P990982 is an CCL17-targeting IgG2κ type human antibody, the recommed isotype control is Human IgG2 kappa, Isotype Control (HY-P99002) .

HY-P990937

Pacibekitug	Interleukin Related	Inflammation/Immunology
HY-P990937 is an IL6-targeting IgG2κ type human antibody, the recommed isotype control is Human IgG2 kappa, Isotype Control (HY-P99002) .

HY-P99893

Rozibafusp alfa AMG-570	CD28 TNF Receptor	Others
Rozibafusp alfa (AMG-570) is a humanized IgG2-κ monoclonal antibody targets ICOSL and BAFF. Prezalumab demonstrates beneficial activities on the arthritis of systemic lupus erythematosus. Prezalumab can be used for the research of sjogren's syndrome cutaneous lupus erythematosus, psoriasis and systemic lupus erythematosus (SLE) ^[2].

HY-P990732

Cepeprubart	Inhibitory Antibodies	Inflammation/Immunology
Cepeprubart is an anti-SELPLG human IgG2 κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990712

Ersodetug	Insulin Receptor	Inflammation/Immunology
Ersodetug is an anti-INSR (insulin receptor) human IgG2 κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990713

Nolavetbart	Interleukin Related	Inflammation/Immunology
Nolavetbart is an anti-Canlupfam IL31RA human IgG2 κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P99729

Melrilimab GSK 3772847; CNTO-7160	Interleukin Related	Inflammation/Immunology
Melrilimab (GSK 3772847) is an IgG2-kappa *anti-IL1RL1/ST2/IL33R/DER4/FIT-1* monoclonal antibody. Melrilimab can be used for the research of asthma .

HY-P990699

Riltovetbart ZTS-00008183	Interleukin Related	Inflammation/Immunology
Riltovetbart is a canine-derived IgG2 κ monoclonal antibody raised against Canlupfam IL13 .

HY-P990407

Anti-EPOR Antibody	Inhibitory Antibodies	Inflammation/Immunology
Anti-EPOR Antibody is a humanized antibody expressed in CHO, targeting EPOR. The predicted molecular weight (MW) of Anti-EPOR Antibody is 150 kDa. The isotype control for Anti-EPOR Antibody can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990587

FR104	CD28	Inflammation/Immunology
FR104 is a humanized antibody expressed in CHO cells that targets CD28. FR104 comprises a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for FR104 can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990662

Sapelizumab	Interleukin Related	Inflammation/Immunology
Sapelizumab is a CHO-expressed humanized antibody targeting IL-6Ra/CD126. Sapelizumab has a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Sapelizumab can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990467

Anti-MICB Antibody	Transmembrane Glycoprotein	Inflammation/Immunology
The Anti-MICB Antibody is a humanized antibody expressed in CHO cells, targeting MICB. The Anti-MICB Antibody contains a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 143.66 kDa. The isotype control for the Anti-MICB Antibody can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990460

Anti-LAP Antibody	TGF-beta/Smad	Inflammation/Immunology
Anti-LAP Antibody is a humanized antibody expressed in CHO cells, targeting LAP. The Anti-LAP Antibody features a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. For isotype control of the Anti-LAP Antibody, you can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P991048

AMG-820	c-Fms	Cancer
AMG-820 is a fully human IgG2 antibody that targets CSF-1R. AMG-820 inhibits binding of the ligands CSF1 and IL34 and subsequent ligand-induced receptor activation. The isotype control for AMG-820 can refer to Human IgG2 kappa, Isotype Control (HY-P99002) .

HY-P990638

NI-0701	CXCR	Inflammation/Immunology
NI-0701 is a humanized antibody expressed in CHO cells that targets CCL5/RANTES. NI-0701 has a huIgG2 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for NI-0701 can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990474

Anti-NGF/bNGF Antibody	Trk Receptor	Inflammation/Immunology
Anti-NGF/bNGF Antibody is a CHO-expressed humanized antibody that targets NGF/bNGF. Anti-NGF/bNGF Antibody has a huIgG2a heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.14 kDa. The isotype control for Anti-NGF/bNGF Antibody can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990597

HuGAL-F2	FGFR	Inflammation/Immunology
HuGAL-F2 is a human-derived antibody expressed in CHO cells, targeting *FGF2. HuGAL-F2 contains a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for HuGAL-F2 can refer to Human IgG2* kappa, Isotype Control (HY-P99002).

HY-P990476

Anti-NOTCH1 Antibody	Notch	Inflammation/Immunology
The Anti-NOTCH1 Antibody is a CHO-expressed human antibody targeting NOTCH1. The Anti-NOTCH1 Antibody has a huIgG2 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for the Anti-NOTCH1 Antibody can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990482

Anti-PAR2 Antibody	Inhibitory Antibodies	Inflammation/Immunology
The Anti-PAR2 Antibody is a human-derived antibody expressed in CHO cells, targeting *PAR2. The Anti-PAR2 Antibody contains a huIgG2 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for the Anti-PAR2 Antibody can be referred to as Human IgG2* kappa, Isotype Control (HY-P99002).

HY-P990656

RG-6125	Inhibitory Antibodies	Inflammation/Immunology
RG-6125 is a humanized antibody expressed in CHO, targeting CDH11/Cadherin-11. RG-6125 has a huIgG2 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for RG-6125 can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990478

Anti-Orai1 Antibody	CRAC Channel	Inflammation/Immunology
Anti-Orai1 Antibody is a humanized antibody expressed in CHO cells that targets Orai1. The Anti-Orai1 Antibody has a huIgG2 heavy chain and a huλ light chain, with an predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-Orai1 Antibody can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990468

Anti-MMP9 Antibody	MMP	Inflammation/Immunology
Anti-MMP9 Antibody is a CHO-expressed human antibody that targets MMP9. The Anti-MMP9 Antibody is composed of a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.76 kDa. For the isotype control of the Anti-MMP9 Antibody, you can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990317

AGS-67E	Transmembrane Glycoprotein	Inflammation/Immunology
AGS-67E is a humanized antibody expressed by CHO, targeting TSPAN26/CD37. AGS-67E has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 143.44 kDa. The isotype control for AGS-67E can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990321

AMG-108 MEDI 8968	Interleukin Related	Inflammation/Immunology
AMG-108 is a humanized antibody expressed in CHO cells, targeting IL-1R1/CD121a. AMG-108 is composed of a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for AMG-108 can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990313

ABX-IL8	CXCR Interleukin Related	Inflammation/Immunology
ABX-IL8 is a human-derived antibody expressed in CHO cells, targeting CXCL8/IL-8. ABX-IL8 contains a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 143.94 kDa. The isotype control for ABX-IL8 can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990528

Anti-TNFRSF7/CD27 Antibody	TNF Receptor	Inflammation/Immunology
Anti-TNFRSF7/CD27 Antibody is a CHO-expressed human antibody targeting TNFRSF7/CD27. The Anti-TNFRSF7/CD27 Antibody contains huIgG2 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-TNFRSF7/CD27 Antibody can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

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