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J774A.1 macrophages

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (2) Endogenous Metabolite (2) Isocitrate Dehydrogenase (IDH) (1) NF-κB (2) NOD-like Receptor (NLR) (1)
By Research Areas:	Cancer (1) Infection (2) Inflammation/Immunology (3)
Oligonucleotides:	Emulsifiers (1)

4

Inhibitors & Agonists

2

Natural
Products

1

Oligonucleotides

Targets Recommended: Macrophage migration inhibitory factor (MIF)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

JC-171	NOD-like Receptor (NLR)	Inflammation/Immunology
JC-171 is a selective NLRP3 inflammasome inhibitor, with an IC₅₀ of 8.45 μM for inhibiting LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages .

Oxalomalic acid trisodium Oxalomalate trisodium	Isocitrate Dehydrogenase (IDH)	Cancer
Oxalomalic acid (Oxalomalate) trisodium is a aconitase and NADP-dependent isocitrate dehydrogenase inhibitor. Oxalomalic acid trisodium inhibits nitrite production and iNOS protein expression in lipopolysaccharide (HY-D1056)-activated J774 macrophages .

Myristic acid 3 Publications Verification	Endogenous Metabolite NF-κB Bacterial	Infection Inflammation/Immunology
Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties .

Myristic acid (Standard)	Endogenous Metabolite NF-κB Bacterial	Infection Inflammation/Immunology
Myristic acid (Standard) is the analytical standard of Myristic acid. This product is intended for research and analytical applications. Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties .

Cat. No.	Product Name		Classification

Myristic acid 3 Publications Verification		Emulsifiers
Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties .

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