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Results for "

J774A.1 macrophages

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

2

Natural
Products

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-117432
    JC-171

    		NOD-like Receptor (NLR) Inflammation/Immunology
    JC-171 is a selective NLRP3 inflammasome inhibitor, with an IC50 of 8.45 μM for inhibiting LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages .
    JC-171
  • HY-131521
    Oxalomalic acid trisodium

    Oxalomalate trisodium

    		 Isocitrate Dehydrogenase (IDH) Cancer
    Oxalomalic acid (Oxalomalate) trisodium is a aconitase and NADP-dependent isocitrate dehydrogenase inhibitor. Oxalomalic acid trisodium inhibits nitrite production and iNOS protein expression in lipopolysaccharide (HY-D1056)-activated J774 macrophages .
    Oxalomalic acid trisodium
  • HY-N2041
    Myristic acid
    3 Publications Verification

    		 Endogenous Metabolite NF-κB Bacterial Infection Inflammation/Immunology
    Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties .
    Myristic acid
  • HY-149992
    MyD88-IN-1

    		MyD88 Inflammation/Immunology Cancer
    MyD88-IN-1 (Compound c17) is an orally active MyD88 inhibitor. MyD88-IN-1 inhibits the interaction of TLR4 and MyD88 and suppressed the NF-κB pathway. MyD88-IN-1 can be used in research of cancer and inflammatory .
    MyD88-IN-1
  • HY-164813
    oxLig-1

    7-Ketocholesteryl-9-carboxynonanoate

    		 NF-κB Metabolic Disease
    oxLig-1 (7-Ketocholesteryl-9-carboxynonanoate) is the lipid moiety of oxidized low-density lipoprotein (oxLDL) and is a key ligand for β-glycoprotein I (β(2)-GPI). oxLig-1 causes nuclear translocation by activating the NF-κB pathway. oxLig-1 can be used in the study of atherosclerosis (AS) .
    oxLig-1
  • HY-N2041R
    Myristic acid (Standard)

    		Endogenous Metabolite NF-κB Bacterial Infection Inflammation/Immunology
    Myristic acid (Standard) is the analytical standard of Myristic acid. This product is intended for research and analytical applications. Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties .
    Myristic acid (Standard)

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