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Results for "

KDM2A

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

2

Natural
Products

2

Recombinant Proteins

1

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108706
    KDM2A/7A-IN-1

    		Histone Demethylase Cancer
    KDM2A/7A-IN-1 is a first-in-class, selective and cell-permeable inhibitor of histone lysine demethylases KDM2A/7A, with an IC50 of 0.16 μM for KDM2A, exhibits 75 fold selevtivity over other JmjC lysine demethylases, and is inactive on methyl transferases, and histone acetyl transferases .
    KDM2A/7A-IN-1
  • HY-13643
    Daminozide
    2 Publications Verification

    		 Histone Demethylase Cancer
    Daminozide, a plant growth regulator, is a selective inhibitor of the human KDM2/7 histone demethylases, with IC50s of 0.55, 1.5 and 2.1 μM for PHF8, KDM2A, and KIAA1718, respectively. Daminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested [2].
    Daminozide
  • HY-12304
    IOX1
    Maximum Cited Publications
    11 Publications Verification

    		 Histone Demethylase Cancer
    IOX1, 5-Carboxy-8-hydroxyquinoline, is a potent broad‐spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 inhibits KDM4C, KDM4E, KDM2A, KDM3A and KDM6B with IC50 values of 0.6 μM, 2.3 μM, 1.8 μM, 0.1 μM and 1.4 μM, respectively [2]. IOX1 also inhibits ALKBH5 .
    IOX1
  • HY-107573
    KDM2/7-IN-1
    1 Publications Verification

    		 Histone Demethylase Cancer
    KDM2/7-IN-1 (TC-E 5002) is a selective histone demethylase KDM2/7 subfamily inhibitor (IC50 values are 0.2, 1.2, 6.8, 55, 83, >100 and >120 μM for KDM7A, KDM7B, KDM2A, KDM5A, KDM4C, KDM6A and KDM4A respectively). KDM2/7-IN-1 inhibits growth of HeLa and KYSE-150 cancer cells in vitro .
    KDM2/7-IN-1
  • HY-RS07209
    KDM2A Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    KDM2A Human Pre-designed siRNA Set A contains three designed siRNAs for KDM2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    KDM2A Human Pre-designed siRNA Set A
    KDM2A Human Pre-designed siRNA Set A
  • HY-13643R
    Daminozide (Standard)

    		Histone Demethylase Cancer
    Daminozide (Standard) is the analytical standard of Daminozide. This product is intended for research and analytical applications. Daminozide, a plant growth regulator, is a selective inhibitor of the human KDM2/7 histone demethylases, with IC50s of 0.55, 1.5 and 2.1 μM for PHF8, KDM2A, and KIAA1718, respectively. Daminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested [2].
    Daminozide (Standard)

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