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KL465

" in MedChemExpress (MCE) Product Catalog:

By Targets:	PROTACs (1)
By Research Areas:	Cancer (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*KL-465*	PROTACs	Cancer
KL-465 is a PROTAC degrader for MAGE-A3, that degrades MAGE-A3 with a DC₅₀ of 2 μM in HeLa cell. KL-465 inhibits viability of MAGE-A3 positive cancer cell HCT116, A375 and HeLa. (Blue: Ligand for E3 ligase (HY-151227); Black: Linker (HY-W679862); Pink: Ligand for target protein (HY-169087))

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