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Results for "

Kir1

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

2

Peptides

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-118607
    VU041

    		Potassium Channel Parasite Infection
    VU041 is a first submicromolar-affinity inhibitor of Anopheles (An.) gambiae and Aedes (Ae.) aegypti inward rectifier potassium 1 (Kir1) channels with IC50 values of 2.5?μM and 1.7?μM, respectively. VU041 inhibits appreciably is mammalian Kir2.1 (IC50 of 12.7?μM), and has less inhibitory effect on mammalian Kir1.1, Kir4.1, Kir6.2/SUR1, and Kir7.1. VU041 also induces impaired Malpighian tubule function [1].
    VU041
  • HY-P1275
    Tertiapin-Q
    2 Publications Verification

    		 Potassium Channel Cardiovascular Disease
    Tertiapin-Q is a highly selective blocker of GIRK1/4 heterodimer and ROMK1 (Kir1.1).
    Tertiapin-Q
  • HY-108585A
    VU591

    		Potassium Channel Neurological Disease
    VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. VU591 can be used for neurological research with HY-108585 (the equivalent of VU591 hydrochloride) [1].
    VU591
  • HY-108585
    VU591 hydrochloride

    		Potassium Channel Neurological Disease
    VU591 hydrochloride is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. VU591 hydrochloride can be used for neurological research with HY-108585A (the equivalent of VU591 hydrochloride) [1].
    VU591 hydrochloride
  • HY-108595
    VU590

    		Potassium Channel Others
    VU590 is a potent and moderately selective ROMK (Kir1.1) inhibitor, with an IC50 of 290 nM. VU590 also inhibits Kir7.1, with an IC50 of 8 μM. VU590 is not a good probe of ROMK function in the kidney [1] .
    VU590
  • HY-P1403
    Tertiapin LQ

    		Potassium Channel Others
    Tertiapin LQ is a specific and reversible renal outer medullary potassium ROMK1 (Kir1.1) channel inhibitor [1].
    Tertiapin LQ
  • HY-110076
    VU590 dihydrochloride

    		Potassium Channel Others
    VU590 dihydrochloride is a potent and moderately selective ROMK (Kir1.1) inhibitor, with an IC50 of 290 nM. VU590 also inhibits Kir7.1, with an IC50 of 8 μM. VU590 dihydrochloride is not a good probe of ROMK function in the kidney [1] .
    VU590 dihydrochloride
  • HY-N2369B
    (-)-Chelidonine

    		Others Others
    (-)-Chelidonine is a Alkaloids product that can be isolated from the herbs of Glaucium squamigerum KAR. et KIR. .
    (-)-Chelidonine

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