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Long-Evans rat

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1986

    4,4'-DDE; p,p'-Dichlorodiphenyldichloroethylene

    Androgen Receptor Drug Metabolite Metabolic Disease Endocrinology
    p,p'-DDE (4,4'-DDE) is the major and persistent metabolite of DDT. p,p'-DDE is a orally active androgen receptor antagonist with an IC50 of 5 μM and a Ki of 3.5 μM. p,p'-DDE can affect the development and function of the male reproductive system. Additionally, high serum concentrations of p,p'-DDE may be a risk factor for type 2 diabetes in women .
    p,p'-DDE
  • HY-N9483

    7-Oxo-DHEA; 7-Ketodehydroepiandrosterone; 7-Oxodehydroepiandrosterone

    GABA Receptor Metabolic Disease
    7-Keto-DHEA binds to GABA Receptor, and reduces the ethanol intake in rats. 7-Keto-DHEA exhibits potential in investigation of alcohol dependence disorders .
    7-Keto-DHEA

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