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Results for "

Mad2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Aurora Kinase (1) CDK (1) Microtubule/Tubulin (1) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (2) Neurological Disease (1)
Oligonucleotides:	Pre-designed siRNA Sets (3) siRNAs (3)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100341

M2I-1	Others	Others
M2I-1 is a *Mad2* inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC) .

HY-13649

Indibulin 1 Publications Verification ZIO 301; D 24851	Microtubule/Tubulin Apoptosis	Neurological Disease Cancer
Indibulin (ZIO 301), an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis .

HY-RS07949

MAD2L1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MAD2L1 Human Pre-designed siRNA Set A contains three designed siRNAs for MAD2L1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MAD2L1 Human Pre-designed siRNA Set A MAD2L1 Human Pre-designed siRNA Set A

HY-RS07951

MAD2L2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MAD2L2 Human Pre-designed siRNA Set A contains three designed siRNAs for MAD2L2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MAD2L2 Human Pre-designed siRNA Set A MAD2L2 Human Pre-designed siRNA Set A

HY-RS07950

MAD2L1BP Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MAD2L1BP Human Pre-designed siRNA Set A contains three designed siRNAs for MAD2L1BP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MAD2L1BP Human Pre-designed siRNA Set A MAD2L1BP Human Pre-designed siRNA Set A

HY-123279

OM137	Aurora Kinase CDK	Cancer
OM137 is an aurora kinase inhibitor, with an IC₅₀ of 21.7 μM (Aurora A kinase) and 2.4 μM (Aurora B kinase). OM137 also inhibits Cdk1/cyclinB and Cdk5/p25 with an approximate IC₅₀ of 20 μM. OM137 reduces spindle checkpoint-signaling proteins (Mad2 and BubR1) at the kinetochores of chromosomes .

Cat. No.	Compare	Product Name	Species	Source

HY-P71540

	MAD2L1 Protein, Human (His-SUMO) HsMad2; Mad 2; Mad2 like 1; Mad2 mitotic arrest deficient like 1; Mad2-like protein 1; Mad2l1; MD2L1_HUMAN; Mitotic arrest deficient 2-like protein 1; Mitotic spindle assembly checkpoint protein Mad2A; REV7	Human	E. coli
	MAD2L1 is a critical spindle assembly checkpoint component that delays anaphase until correct chromosome alignment. During prophase, it forms a heterotetrameric complex with MAD1L1 at unattached kinetochores, recruiting O-MAD2 and aiding transformation. MAD2L1 Protein, Human (His-SUMO) is the recombinant human-derived MAD2L1 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

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HY-P83318

	MAD2L1 Binding Protein Antibody (YA3063) Mad2L1BP; CMT2; KIAA0110; Mad2L1-binding protein; Caught by Mad2 protein	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	MAD2L1 Binding Protein Antibody (YA3063) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3063), targeting MAD2L1 Binding Protein, with a predicted molecular weight of 31 kDa (observed band size: 34 kDa). MAD2L1 Binding Protein Antibody (YA3063) can be used for WB, IHC-P, ICC/IF experiment in human, mouse, rat background.

HY-P81947

	MAD2L1 Antibody (YA1692) Mad2L1; Mad2; Mitotic spindle assembly checkpoint protein Mad2A; HsMad2; Mitotic arrest deficient 2-like protein 1; Mad2-like protein 1	WB	Human
	MAD2L1 Antibody (YA1692) is a biotin-conjugated non-conjugated IgG antibody, targeting MAD2L1, with a predicted molecular weight of 24 kDa (observed band size: 24 kDa). MAD2L1 Antibody (YA1692) can be used for WB experiment in human background.

HY-P83445

	MAD2L2 Antibody (YA3190) REV7; FANCV; Mad2B; POLZ2	WB, ICC/IF, IP	Human
	MAD2L2 Antibody (YA3190) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3190), targeting MAD2L2, with a predicted molecular weight of 24 kDa (observed band size: 24 kDa). MAD2L2 Antibody (YA3190) can be used for WB, ICC/IF, IP experiment in human background.

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Cat. No.	Product Name		Classification

HY-RS07949

MAD2L1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
MAD2L1 Human Pre-designed siRNA Set A contains three designed siRNAs for MAD2L1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS07951

MAD2L2 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
MAD2L2 Human Pre-designed siRNA Set A contains three designed siRNAs for MAD2L2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS07950

MAD2L1BP Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
MAD2L1BP Human Pre-designed siRNA Set A contains three designed siRNAs for MAD2L1BP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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