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Mer-NF5003F

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-137985
    Mer-NF5003F

    Stachybotrydial; F 1839M; Stachybotrydial

    		 HSV Infection
    Mer-NF5003F is a sesquiterpene originally isolated from Stachybotrys with diverse biological activities. It inhibits avian myeloblastosis virus (AMV) protease (IC50=7.8 μM).1 Mer-NF5003F inhibits sialyltransferase 6N (ST6N), ST3O, and ST3N (IC50s=0.61, 6.7, and 10 μg/mL, respectively), as well as fucosyltransferase (IC50=11.3 μg/mL). It is active against herpes simplex virus 1 (HSV-1) in vitro (IC50=4.32 μg/mL).3 Mer-NF5003F is also active against the multidrug-resistant P. falciparum strain K1 (IC50=0.85 μg/mL).
    Mer-NF5003F

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