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N-tert-Butyl-α-phenylnitrone

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Angiotensin Receptor (1) Bacterial (1) Biochemical Assay Reagents (1) Cathepsin (1) CD38 (1) COX (2) Endothelin Receptor (1) Fluorescent Dye (1) Histone Methyltransferase (1) Reactive Oxygen Species (2)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (1) Metabolic Disease (2) Neurological Disease (1)

Inhibitors & Agonists

Peptides

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-128463

**N-tert-Butyl-α-phenylnitrone** 1 Publications Verification	COX Reactive Oxygen Species	Neurological Disease Metabolic Disease Inflammation/Immunology
N-tert-Butyl-α-phenylnitrone is a nitrone-based free radical scavenger that forms nitroxide spin adducts. N-tert-Butyl-α-phenylnitrone inhibits COX2 catalytic activity. N-tert-Butyl-α-phenylnitrone has potent ROS scavenging, anti-inflammatory, neuroprotective, anti-aging and anti-diabetic activities, and can penetrate the blood-brain barrier .

HY-P4545

*Abz-Gly-p-nitro-Phe-Pro-OH*	Angiotensin Receptor	Others
Abz-Gly-p-nitro-Phe-Pro-OH is the fluorescent substrate angiotensin I converting enzyme (ACE-I) with 355 nm excitation and 405 nm emission wavelengths .

HY-P4725

*Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2*	Fluorescent Dye	Others
Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 is a fluorogenic substrate, that can be used for the fluorescence screening assay .

HY-128463S

N-tert-Butyl-α-phenylnitrone-d14	COX Reactive Oxygen Species	Metabolic Disease
N-tert-Butyl-α-phenylnitrone-d₁₄ is the deuterium labeled N-tert-Butyl-α-phenylnitrone[1]. N-tert-Butyl-α-phenylnitrone is a nitrone-based free radical scavenger that forms nitroxide spin adducts. N-tert-Butyl-α-phenylnitrone inhibits COX2 catalytic activity. N-tert-Butyl-α-phenylnitrone has potent ROS scavenging, anti-inflammatory, neuroprotective, anti-aging and anti-diabetic activities, and can penetrate the blood-brain barrier[2][3][4][5].

HY-P4561

*H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH*	Cathepsin	Others
H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .

HY-P4556

*H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe*	Biochemical Assay Reagents	Others
H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is a polypeptide that can be hydrolyzed by Rennin (HY-P2810). H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is commonly used as a biochemical reaction reagent .

HY-100832A

UNC3866 TFA	Histone Methyltransferase	Cancer
UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC₅₀=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.

HY-P3350

LS-BF1	Bacterial	Infection
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

Cat. No.	Product Name	Target	Research Area

HY-P4545

*Abz-Gly-p-nitro-Phe-Pro-OH*	Angiotensin Receptor	Others
Abz-Gly-p-nitro-Phe-Pro-OH is the fluorescent substrate angiotensin I converting enzyme (ACE-I) with 355 nm excitation and 405 nm emission wavelengths .

HY-P4725

*Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2*	Fluorescent Dye	Others
Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 is a fluorogenic substrate, that can be used for the fluorescence screening assay .

HY-P4561

*H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH*	Cathepsin	Others
H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .

HY-P4556

*H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe*	Biochemical Assay Reagents	Others
H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is a polypeptide that can be hydrolyzed by Rennin (HY-P2810). H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is commonly used as a biochemical reaction reagent .

HY-100832A

UNC3866 TFA	Histone Methyltransferase	Cancer
UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC₅₀=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.

HY-P3350

LS-BF1	Bacterial	Infection
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

Cat. No.	Product Name	Chemical Structure

HY-128463S

N-tert-Butyl-α-phenylnitrone-d14
N-tert-Butyl-α-phenylnitrone-d₁₄ is the deuterium labeled N-tert-Butyl-α-phenylnitrone[1]. N-tert-Butyl-α-phenylnitrone is a nitrone-based free radical scavenger that forms nitroxide spin adducts. N-tert-Butyl-α-phenylnitrone inhibits COX2 catalytic activity. N-tert-Butyl-α-phenylnitrone has potent ROS scavenging, anti-inflammatory, neuroprotective, anti-aging and anti-diabetic activities, and can penetrate the blood-brain barrier[2][3][4][5].

N-tert-Butyl-α-phenylnitrone-d14

N-tert-Butyl-α-phenylnitrone-d₁₄ is the deuterium labeled N-tert-Butyl-α-phenylnitrone[1]. N-tert-Butyl-α-phenylnitrone is a nitrone-based free radical scavenger that forms nitroxide spin adducts. N-tert-Butyl-α-phenylnitrone inhibits COX2 catalytic activity. N-tert-Butyl-α-phenylnitrone has potent ROS scavenging, anti-inflammatory, neuroprotective, anti-aging and anti-diabetic activities, and can penetrate the blood-brain barrier[2][3][4][5].

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