2. Epigenetics
  3. Histone Methyltransferase
  4. UNC3866 TFA

UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC50=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

UNC3866 TFA Chemical Structure

UNC3866 TFA Chemical Structure

CAS No. : 1872382-48-3

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UNC3866 TFA Related Antibodies

Top Publications Citing Use of Products

View All Histone Methyltransferase Isoform Specific Products:

View All Isoforms
EZH1 EZH2 DOT1L SMYD2 SMYD3 SUV39H2/KMT1B EHMT2/G9a/KMT1C EHMT1/GLP/KMT1D SETDB1/KMT2G SETD2/KMT3A NSD2/MMSET/WHSC1 SETD7/KMT7 SETD8/KMT5A PRMT1 PRMT3 PRMT4 PRMT5 PRMT6 PRMT7 PRMT8

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Description

UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC50=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.

Molecular Weight

909.04

Formula

C45H67F3N6O10
CAS No.
Sequence

{Phe<P-tert-butylbenzoyl>}-Ala-Leu-{Lys<Et,Et>}-{Ser<Me>}
Sequence Shortening

{Phe<P-tert-butylbenzoyl>}-AL-{Lys<Et,Et>}-{Ser<Me>}
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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UNC3866 TFA Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UNC38661872382-48-3UNC 3866UNC-3866Histone MethyltransferaseInhibitorinhibitorinhibit

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