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Results for "

PANK

" in MedChemExpress (MCE) Product Catalog:

By Targets:	PANK (5) Small Interfering RNA (siRNA) (4)
By Research Areas:	Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (2)
Oligonucleotides:	Human Pre-designed siRNA Sets (4) siRNAs (4)

Inhibitors & Agonists

Targets Recommended: PANK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Pantothenate kinase-IN-2	PANK	Metabolic Disease
Pantothenate kinase-IN-2 is a potent Pantothenate kinase 1/3 (PanK1/3) inhibitor with an IC₅₀ of 0.14 μM and 0.36 μM. Pantothenate kinase-IN-2 is a promising agent for PKAN (PanK-associated neurodegeneration) and diabetes research .

PZ-2891 1 Publications Verification	PANK	Neurological Disease
PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC₅₀s of 40.2 nM, 0.7 nM and 1.3 nM, respectively .

PANK1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PANK1 Human Pre-designed siRNA Set A contains three designed siRNAs for PANK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PANK1 Human Pre-designed siRNA Set A PANK1 Human Pre-designed siRNA Set A

PANK3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PANK3 Human Pre-designed siRNA Set A contains three designed siRNAs for PANK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PANK3 Human Pre-designed siRNA Set A PANK3 Human Pre-designed siRNA Set A

PANK4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PANK4 Human Pre-designed siRNA Set A contains three designed siRNAs for PANK4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PANK4 Human Pre-designed siRNA Set A PANK4 Human Pre-designed siRNA Set A

PANK2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PANK2 Human Pre-designed siRNA Set A contains three designed siRNAs for PANK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PANK2 Human Pre-designed siRNA Set A PANK2 Human Pre-designed siRNA Set A

Claziprotamidum Claziprotamide	PANK	Others
Claziprotamidum (Claziprotamide) is a pantothenate kinases 1 and 3 (PanK1 and PanK3) positive allosteric modulator (PAM) .

Pantothenate kinase-IN-1	PANK	Neurological Disease
Pantothenate kinase-IN-1 (Compound 1) is a pantothenate kinase (PANK) modulator with an IC₅₀ of 0.51 µM against *PANK3*. Pantothenate kinase-IN-1 has a reasonable ligand efficiency (LipE = 2.8) .

PZ-3022	PANK	Inflammation/Immunology
PZ-3022 is an orally active and allosteric *PanK* activator that counteracts C3-CoA inhibition. PZ-3022 increases hepatic CoASH and C2-CoA and decreases C3-CoA in the propionic acidemia mouse model. PZ-3022 can be used for research of mitochondrial defect in propionic acidemia .

PANK1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PANK1 Human Pre-designed siRNA Set A contains three designed siRNAs for PANK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PANK3 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PANK3 Human Pre-designed siRNA Set A contains three designed siRNAs for PANK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PANK4 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PANK4 Human Pre-designed siRNA Set A contains three designed siRNAs for PANK4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PANK2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PANK2 Human Pre-designed siRNA Set A contains three designed siRNAs for PANK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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