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Results for "

PHB1

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Natural
Products

1

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-114989
    Fluorizoline
    1 Publications Verification

    Apoptosis Cancer
    Fluorizoline selectively and directly binds to prohibitin 1 (PHB1) and 2 (PHB2), and induces apoptosis. Fluorizoline reduces chronic lymphocytic leukemia (CLL) cell viability through the upregulation of NOXA and BIM. Fluorizoline exerts antitumor action in a p53-independent manner [1].
    Fluorizoline
  • HY-RS10407

    Small Interfering RNA (siRNA) Others

    PHB1 Human Pre-designed siRNA Set A contains three designed siRNAs for PHB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PHB1 Human Pre-designed siRNA Set A
    PHB1 Human Pre-designed siRNA Set A
  • HY-162904

    Others Cardiovascular Disease
    BPU17 binds to PHB1 and causes mild defects in mitochondrial function by defects in the PHB1-PHB2 interaction. This impairment inhibits the SRF/CArG-box-dependent transcription, resulting in the suppression of epithelial-mesenchymal transition (EMT) of retinal pigment epithelial cells (RPEs). BPU17 exhibits antifibrotic activity in vivo. BPU17 is promising for research of anti-neovascular age-related macular degeneration (nAMD) agent [1].
    BPU17
  • HY-141475

    Endogenous Metabolite Others
    Acetoacetyl coenzyme A sodium is a central endogenous metabolite. The Km at pH 7.5 for Acetoacetyl coenzyme A sodium is 1.10 mM. Acetoacetyl coenzyme A sodium can be used for the synthesis of phosphotransbutyrylase (PTB) and poly-3-hydroxybutyrate (PHB) .
    Acetoacetyl coenzyme A sodium

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