PVR

By Targets:	Endogenous Metabolite (2) Phosphodiesterase (PDE) (1) Small Interfering RNA (siRNA) (1) Thyroid Hormone Receptor (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Endocrinology (1)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-A0070A

Liothyronine 20+ Cited Publications Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3	Thyroid Hormone Receptor Endogenous Metabolite	Endocrinology Cancer
Liothyronine is an active form of thyroid hormone. Liothyronine binds to thyroid hormone receptors TRα and TRβ with K_is of 2.33 and 2.29 nM for hTRα and hTRβ, respectively. Liothyronine also binds to PVR and blocks the interaction of TIGIT/PVR .

HY-RS11473

PVR Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PVR Human Pre-designed siRNA Set A contains three designed siRNAs for PVR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PVR Human Pre-designed siRNA Set A PVR Human Pre-designed siRNA Set A

HY-112352

SU9518	Endogenous Metabolite	Others
SU9518 is a tyrosine kinase inhibitor with specific activity against PDGFRα. SU9518 can inhibit the development of proliferative vitreoretinopathy (PVR) in fibroblast and Muller cell rabbit models. SU9518 showed effective inhibitory effects in these models without toxic effects. Therefore, SU9518 has the potential to be used to inhibit PVR in humans and other proliferative eye diseases involving fibrosis and gliosis .

HY-14252A

Milrinone lactate Win 47203 lactate	Phosphodiesterase (PDE)	Cardiovascular Disease
Milrinone lactate is a potent inotropic dilating agent. Milrinone lactate shows simultaneous positive inotropic and vasodilating activities. Milrinone lactate promotes reduction of SVR and PVR in patients with DCM and NYHA class III and IV of heart failure. Milrinone lactate has the potential for the research of cardiovascular function after cardiac surgery and in septic shock .

Cat. No.	Product Name	Target	Research Area

HY-P99763

Ociperlimab BGB-A1217	Inhibitory Antibodies	Cancer
Ociperlimab is a humanized IgG1 anti-TIGIT antibody. Ociperlimab binds to the extracellular domain of human TIGIT with high affinity (K_D = 0.135 nM). Ociperlimab blocks the interaction between TIGIT and its ligands PVR or PVR-L2. Ociperlimab can be used in research of cancer .

HY-P99949

Etigilimab OMP-313M32	Inhibitory Antibodies	Cancer
Etigilimab (OMP-313M32), a humanized IgG1 monoclonal antibody, blocks TIGIT interaction with PVR (CD155; poliovirus receptor) and inhibits downstream signalling with target cell killing .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-A0070A

Liothyronine 20+ Cited Publications Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3	Structural Classification Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Phenols Endocrine diseases Endogenous metabolite Disease Research Fields Endocrinology	Thyroid Hormone Receptor Endogenous Metabolite
Liothyronine is an active form of thyroid hormone. Liothyronine binds to thyroid hormone receptors TRα and TRβ with K_is of 2.33 and 2.29 nM for hTRα and hTRβ, respectively. Liothyronine also binds to PVR and blocks the interaction of TIGIT/PVR .

Species:	Human (7) Rhesus Macaque (1) Mouse (1) Rat (1)
Tag:	His (6) Tag Free (1) Avi (3) Fc (3)
Source:	HEK293 (10)

Cat. No.	Compare	Product Name	Species	Source

HY-P7789

	PVR/CD155 Protein, Mouse (HEK293, His) rMuCD155, His; Poliovirus receptor; CD155 antigen; Nectin-like protein 5; Nectin-2; Tage4 receptor; PVR; CD155	Mouse	HEK293
	PVR/CD155 Protein, Mouse (HEK293, His) is a recombinant mouse CD155 expressed in HEK 293 cells with a His tag at the N-terminus. CD155 Protein plays a role in cancer cell invasion and migration.

HY-P70807

	PVR/CD155 Protein, Human (HEK293, His) Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS	Human	HEK293
	PVR/CD155 Protein, Human (HEK293, His) is a recombinant Human PVR expressed in HEK 293 cells with a His tag at the N-terminus. PVR, Human plays a role in cancer cell invasion and migration.

HY-P76774

	PVR/CD155 Protein, Rat (HEK293, His) Poliovirus receptor; Nectin-like protein 5; NECL-5; CD155; PVR; PVS	Rat	HEK293
	The PVR/CD155 protein, encoded by the PVR gene, acts as a receptor for poliovirus. It is involved in the regulation of heterophilic and homophilic cell adhesion, as well as leukocyte-mediated cytotoxicity. PVR/CD155 Protein, Rat (HEK293, His) is the recombinant rat-derived PVR/CD155 protein, expressed by HEK293 , with C-His labeled tag. The total length of PVR/CD155 Protein, Rat (HEK293, His) is 319 a.a., with molecular weight of ~54 -75 kDa.

HY-P7790

	PVR/CD155 Protein, Rhesus macaque (HEK293, His) rRhCD155, His; Poliovirus receptor; CD155 antigen; Nectin-like protein 5; Nectin-2; Tage4 receptor; PVR; CD155	Rhesus Macaque	HEK293
	PVR/CD155 Protein, Rhesus macaque (HEK293, His) is a recombinant rhesus macaque CD155 expressed in HEK 293 cells with a His tag at the N-terminus. CD155 Protein plays a role in cancer cell invasion and migration.

HY-P75614

	PVR/CD155 Protein, Human (HEK293) Poliovirus receptor; Nectin-like protein 5; NECL-5; CD155; PVR; PVS	Human	HEK293
	The PVR/CD155 protein plays a key role in initiating natural killer (NK) cell effector functions by binding to CD96 and CD226 receptors. These interactions form mature immune synapses that trigger adhesion, lytic granule secretion, interferon-γ (IFN-γ), and cytotoxicity of activated NK cells. PVR/CD155 Protein, Human (HEK293) is the recombinant human-derived PVR/CD155 protein, expressed by HEK293 , with tag free.

HY-P78084

	PVR/CD155 Protein, Human (Biotinylated, HEK293, His-Avi) 1 Publications Verification CD155; HVED; NECL5; Necl-5; nectin-like 5; PVR; PVS; Tage4; PVSFLJ25946; FLJ25946	Human	HEK293
	The PVR/CD155 protein plays a key role in initiating natural killer (NK) cell effector functions by binding to CD96 and CD226 receptors. These interactions form mature immune synapses that trigger adhesion, lytic granule secretion, interferon-γ (IFN-γ), and cytotoxicity of activated NK cells. PVR/CD155 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived PVR/CD155 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P7401

	PVR/CD155 Protein, Human (HEK293, Fc) rHuPVR/CD155, Fc Chimera; Poliovirus receptor; NECL-5; PVS	Human	HEK293
	PVR/CD155 Protein, Human (HEK293, Fc), a Type I transmembrane glycoprotein in the immunoglobulin superfamily, is involved in the cellular poliovirus infection in primates and intestinal humoral immune responses.

HY-P78400

	PVR/CD155 Protein, Human (HEK293, mFc) CD155; HVED; NECL5; Necl-5; nectin-like 5; PVR; PVS; Tage4; PVSFLJ25946; FLJ25946	Human	HEK293
	The PVR/CD155 protein plays a key role in initiating natural killer (NK) cell effector functions by binding to CD96 and CD226 receptors. These interactions form mature immune synapses that trigger adhesion, lytic granule secretion, interferon-γ (IFN-γ), and cytotoxicity of activated NK cells. PVR/CD155 Protein, Human (HEK293, mFc) is the recombinant human-derived PVR/CD155 protein, expressed by HEK293 , with C-mFc labeled tag.

HY-P78402

	PVR/CD155 Protein, Human (HEK293, His-Avi) CD155; HVED; NECL5; Necl-5; nectin-like 5; PVR; PVS; Tage4; PVSFLJ25946; FLJ25946	Human	HEK293
	The PVR/CD155 protein plays a key role in initiating natural killer (NK) cell effector functions by binding to CD96 and CD226 receptors. These interactions form mature immune synapses that trigger adhesion, lytic granule secretion, interferon-γ (IFN-γ), and cytotoxicity of activated NK cells. PVR/CD155 Protein, Human (HEK293, His-Avi) is the recombinant human-derived PVR/CD155 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P78082

	PVR/CD155 Protein, Human (Biotinylated, HEK293, Fc-Avi) CD155; HVED; NECL5; Necl-5; nectin-like 5; PVR; PVS; Tage4; PVSFLJ25946; FLJ25946	Human	HEK293
	The PVR/CD155 protein plays a key role in initiating natural killer (NK) cell effector functions by binding to CD96 and CD226 receptors. These interactions form mature immune synapses that trigger adhesion, lytic granule secretion, interferon-γ (IFN-γ), and cytotoxicity of activated NK cells. PVR/CD155 Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived PVR/CD155 protein, expressed by HEK293 , with C-hFc and Avi labeled tag.

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HY-P81740

	CD155 Antibody (YA1485) PVR; PVS; Poliovirus receptor; Nectin-like protein 5; NECL-5; CD155	FC, ELISA	Human
	CD155 Antibody (YA1485) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1485), targeting CD155. CD155 Antibody (YA1485) can be used for FC, ELISA experiment in human background.

HY-P82811

	Poliovirus Receptor Antibody (YA2556) PVR; PVS; Poliovirus receptor; Nectin-like protein 5; NECL-5; CD155	WB, IP	Human
	Poliovirus Receptor Antibody (YA2556) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2556), targeting Poliovirus Receptor, with a predicted molecular weight of 45 kDa (observed band size: 70 kDa). Poliovirus Receptor Antibody (YA2556) can be used for WB, IP experiment in human background.

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Cat. No.	Product Name		Classification

HY-RS11473

PVR Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PVR Human Pre-designed siRNA Set A contains three designed siRNAs for PVR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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PVR

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