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Results for "

Phosphodiesterase-IN-2

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Peptides

2

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0579
    Fraxin
    3 Publications Verification

    Fraxoside

    		 Phosphodiesterase (PDE) Inflammation/Immunology
    Fraxin isolated from Cortex Fraxini, is a glucoside of fraxetin and reported to exert potent anti-oxidative stress action , anti-inflammatory and antimetastatic properties. Fraxin shows its antioxidative effect through inhibition of cyclo AMP phosphodiesterase enzyme .
    Fraxin
  • HY-100530D
    Rp-cAMPS sodium salt
    3 Publications Verification

    		 PKA Neurological Disease
    Rp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 µM and 4.5 µM, respectively) antagonist. Rp-cAMPS sodium salt is resistant to hydrolysis by phosphodiesterases .
    Rp-cAMPS sodium salt
  • HY-161663
    Phosphodiesterase-IN-2

    		Phosphodiesterase (PDE) Cardiovascular Disease
    Phosphodiesterase-IN-2 (Compound C7) is a selective, orally active inhibitor for phosphodiesterase 10A (PDE10A), with an IC50 of 11.9 nM. Phosphodiesterase-IN-2 improves the stability of liver microsomes, and lowers BBB permeability. Phosphodiesterase-IN-2 exhibits good pharmacokinetic characters, and attenuates isoprenaline (HY-108353)-induced cardiac hypertrophic in mouse models .
    Phosphodiesterase-IN-2
  • HY-100530A
    Rp-cAMPS

    		PKA Neurological Disease
    Rp-cAMPS, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS is resistant to hydrolysis by phosphodiesterases .
    Rp-cAMPS
  • HY-100530
    Rp-cAMPS triethylammonium salt

    		PKA Neurological Disease
    Rp-cAMPS triethylammonium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS triethylammonium salt is resistant to hydrolysis by phosphodiesterases .
    Rp-cAMPS triethylammonium salt
  • HY-N0579R
    Fraxin (Standard)

    		Phosphodiesterase (PDE) Inflammation/Immunology
    Fraxin (Standard) is the analytical standard of Fraxin. This product is intended for research and analytical applications. Fraxin isolated from Cortex Fraxini, is a glucoside of fraxetin and reported to exert potent anti-oxidative stress action , anti-inflammatory and antimetastatic properties. Fraxin shows its antioxidative effect through inhibition of cyclo AMP phosphodiesterase enzyme .
    Fraxin (Standard)
  • HY-137646
    Sp-2-Cl-cAMPS

    		PKA Parasite Infection
    Sp-2-Cl-cAMPS is an agonist for PKA with improved membrane permeability and stability to phosphodiesterase. Sp-2-Cl-cAMPS exhibits antimalarial activity, and inhibits the proliferation of Plasmodium falciparum with an EC50 of 4 μM. Sp-2-Cl-cAMPS binds to purified P. falciparum PfPKAr (regulatory subunit of PfPKA) with a Ki of 1.3 µM .
    Sp-2-Cl-cAMPS

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