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Results for "

Pomalidomide-amido-PEG3-C2-NH2

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Fluorescent Dye

5

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-130521
    Pomalidomide-amido-PEG3-C2-NH2

    Cereblon Ligand-Linker Conjugates 22; E3 ligase Ligand-Linker Conjugates 55

    		 E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 22) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology .
    Pomalidomide-amido-PEG3-C2-NH2
  • HY-P1003
    Ac-DEVD-AMC
    4 Publications Verification

    		 Fluorescent Dye Others
    Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .
    Ac-DEVD-AMC
  • HY-P1005
    Ac-DEVD-AFC
    5+ Cited Publications

    		 Fluorescent Dye Cancer
    Ac-DEVD-AFC is a fluorogenic substrate (λex=400 nm, λem=530 nm).
    Ac-DEVD-AFC
  • HY-169232
    PCC16 chloride

    		PROTACs Cancer
    PCC16 chloride is a CRBN-based cp-PCC with an IC50 value of 102 nM for the degradation of DHHC3. PCC16 chloride has antitumor activity. (Target protein ligand: HY-169235, linker: HY-169236, E3 ligase ligand: HY-10984) .
    PCC16 chloride
  • HY-P10319
    RI-STAD-2

    		PKA Cardiovascular Disease Cancer
    RI-STAD-2 is a high-affinity interfering peptide that regulates the subunit RI of protein kinase A (PKA). RI-STAD-2 interferes with the binding of AKAPs and PKA-RI by simulating the interaction between AKAPs' α-helix domain and PKA-RI's dimerization/anchoration (D/D) domain, thereby affecting PKA activity and intracellular localization. RI-STAD-2 can be used to study the role of AKAPs interaction with PKA-RI in pathological processes such as cardiovascular disease and cancer .
    RI-STAD-2

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