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SAO

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2861
    Sarcosine oxidase, Bacillus

    SAO

    		 Endogenous Metabolite Others
    Sarcosine oxidase, Bacillus (SAO) can catalyze the oxidative demethylation of sarcosine to generate glycine, H2O2, 5,10-CH2-tetrahydrofolate, which are often used in biochemical reactions .
    Sarcosine oxidase, Bacillus
  • HY-116926
    Deoxynybomycin

    		Antibiotic Bacterial DNA/RNA Synthesis Topoisomerase Apoptosis Infection Cancer
    Deoxynybomycin is an antibiotic, that can be isolated from Streptomyces, and antibacterial activity against Staphylococcus aureus. Deoxynybomycin is the inhibitor for DNA gyrase and Topoisomerase I. Deoxynybomycin induces expression of p21/WAF1, exhibits cytotoxicity and induces apoptosis in cancer cells Saos-2, TMK-1, and THP-1 .
    Deoxynybomycin
  • HY-15048
    GPI 15427

    		PARP Inflammation/Immunology
    GPI 15427 is a potent inhibitor of the enzyme poly (ADP-ribose) polymerase-1 (PARP-1), which plays a harmful role during inflammation. In a rat model of gut injury and inflammation, including splanchnic artery occlusion (SAO) shock and dinitrobenzene sulfonic acid (DNBS)-induced colitis, GPI 15427 demonstrated strong anti-inflammatory effects. It reduced inflammatory cell infiltration, histological injury, and delayed clinical signs of inflammation. GPI 15427 also diminished the accumulation of poly (ADP-ribose) in the ileum and colon of treated rats. These results suggest GPI 15427 could be useful for treating intestinal ischemia and inflammation .
    GPI 15427

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