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Results for "

SBP

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

1

Peptides

2

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-132969
    SBP-3264
    1 Publications Verification

    		 Fluorescent Dye Cancer
    SBP-3264 is a valuable chemical probe for understanding the roles of STK3 and STK4 in acute myeloid leukemia (AML).
    SBP-3264
  • HY-137742
    SBP-7455

    		ULK Autophagy Cancer
    SBP-7455 is a potent, high affinity and orally active dual ULK1/ULK2 autophagy inhibitor with IC50s of 13 nM and 476 nM in the ADP-Glo assays, respectively. SBP-7455 potently inhibits ULK1/2 enzymatic activity and can be used for triple-negative breast cancer (TNBC) research .
    SBP-7455
  • HY-125378
    SBP-0636457

    SBI-0636457; SB1-0636457

    		 IAP Cancer
    SBP-0636457 (SB1-0636457) is a SMAC mimetic, and as an IAP antagonist. SBP-0636457 binds to the BIR-domains of the IAP proteins, with a Ki of 0.27 μM. SBP-0636457 can be used for the research of solid tumors and hematologic cancers .
    SBP-0636457
  • HY-132822
    Ivospemin

    SBP-101

    		 Others Cancer
    Ivospemin (SBP-101) is an antineoplastic spermine analog. Ivospemin has shown efficacy in slowing pancreatic and ovarian tumor progression in vitro and in vivo. Ivospemin shows modest induction of polyamine catabolism, but stronger repression of ornithine decarboxylase activity. Ivospemin is promising for research of cancers .
    Ivospemin
  • HY-125378A
    (7R)-SBP-0636457

    (7R)-SBI-0636457; (7R)-SB1-0636457

    		 IAP Cancer
    (7R)-SBP-0636457 is the isomer of SBP-0636457 (HY-125378), and can be used as an experimental control. SBP-0636457 (SB1-0636457) is a SMAC mimetic, and as an IAP antagonist. SBP-0636457 binds to the BIR-domains of the IAP proteins, with a Ki of 0.27 μM. SBP-0636457 can be used for the research of solid tumors and hematologic cancers .
    (7R)-SBP-0636457
  • HY-147507
    SBP-1

    		Fluorescent Dye Others
    SBP-1 is a sulfite bioluminescent probe (SBP). SBP-1 exhibits the excellent responsivity, selectivity and sensitivity towards sulfite. The recognition of SBP-1 towards sulfite is based on the mechanism of a sulfite-mediated intramolecular cleavage reaction. SBP-1 can be used for detection of exogenous and endogenous sulfite in living animal. SBP-1 also possesses a capability for quantitatively detecting sulfite within a certain concentration range in solution .
    SBP-1
  • HY-147508
    SBP-2

    		Fluorescent Dye Others
    SBP-2 is a sulfite bioluminescent probe (SBP). The recognition of SBP-2 towards sulfite is based on the mechanism of a sulfite-mediated intramolecular cleavage reaction .
    SBP-2
  • HY-147509
    SBP-3

    		Fluorescent Dye Others
    SBP-3 is a sulfite bioluminescent probe (SBP). The recognition of SBP-3 towards sulfite is based on the mechanism of a sulfite-mediated intramolecular cleavage reaction .
    SBP-3
  • HY-P5827
    SBP1 peptide

    		SARS-CoV Angiotensin-converting Enzyme (ACE) Infection
    SBP1 peptide is a chemically synthesized 23-mer peptide fragment of the ACE2 PD α1 helix. SBP1 peptide associates with micromolar affinity to insect-derived SARS-CoV-2-RBD protein .
    SBP1 peptide
  • HY-131189
    N-Boc-SBP-0636457-OH

    		Ligands for E3 Ligase Cancer
    N-Boc-SBP-0636457-OH, a ligand for E3 ubiquitin ligase, is used in the recruitment of IAP E3 ligases. N-Boc-SBP-0636457-OH can be connected to the ligand for Bcl-xL by a linker to form PROTAC Bcl-xL degrader-1 (HY-131188).
    N-Boc-SBP-0636457-OH
  • HY-131190
    N-Boc-SBP-0636457-O-C3-COOH

    		E3 Ligase Ligand-Linker Conjugates Cancer
    N-Boc-SBP-0636457-OH is a synthesized E3 ligase ligand-linker conjugate that incorporates IAP ligand and a linker. N-Boc-SBP-0636457-OH can be used to design a PROTAC Bcl-xL degrader-1 (HY-131188) .
    N-Boc-SBP-0636457-O-C3-COOH
  • HY-114250
    Cantrixil

    TRX-E-002-1

    		 Apoptosis Cancer
    Cantrixil (TRX-E-002-1), an active enantiomer of TRX-E-002, is a second-generation super-benzopyran (SBP) compound. Cantrixil increases phosphorylated c-Jun levels resulting in caspase-mediated apoptosis in ovarian cancer cells. Cantrixil has potent pan anti-cancer activity against a broad range of cancer phenotypes .
    Cantrixil

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