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SNU-C4 HiBiT-PXR KI cells

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-169264
    SJYHJ-026

    		PROTACs Cancer
    SJYHJ-026 (compound 37) is a pregnane X receptor (PXR) degrader with the DC50 of 86.6 nM and maximal degradation of 66.4%. SJYHJ-026 shows cell cytotoxic aganist SNU-C4 HiBiT-PXR KI cells with the IC50 values of 97.4 μM (24 h) and 99.5 μM (72 h) (Blue: VHL ligand HY-125845,Black: linker HY-43048；Pink: PXR inhibitor HY-169277) .
    SJYHJ-026
  • HY-169277
    PXR Ligand 1

    		Others Others
    PXR Ligand 1 is a PXR Ligand and can be used for synthesis of SJYHJ-026 (HY-169264) PROTACs .
    PXR Ligand 1

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