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Results for "

SS-DNA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	DNA Stain (2) DNA/RNA Synthesis (3) Biochemical Assay Reagents (3) Fluorescent Dye (2) Liposome (1) MicroRNA (1) Nucleoside Antimetabolite/Analog (1) Parasite (3) RAD51 (2) SARS-CoV (6)
By Research Areas:	Cancer (6) Infection (6)
Click Chemistry:	Azide (1) Tetrazine (1)
Oligonucleotides:	Aptamers (2)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Click Chemistry

Oligonucleotides

Targets Recommended: DNA-PK DNA Methyltransferase DNA Stain DNA Alkylator/Crosslinker DNA/RNA Synthesis

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-110286

6-Hydroxy-DOPA	DNA/RNA Synthesis	Cancer
6-Hydroxy-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer .

HY-150622

SARS-CoV-2 nsp13-IN-1	SARS-CoV	Infection
SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent nsp13 (non-structural protein 13) inhibitor. SARS-CoV-2 nsp13-IN-1 only inhibits *nsp13 ssDNA* ⁺ ATPase, with an IC₅₀** of 6 μM. SARS-CoV-2 nsp13-IN-1 does not inhibit ssDNA ^- ATPase. SARS-CoV-2 nsp13-IN-1 can be used for COVID-19 research .

HY-P2773

Nuclease S1, Aspergillus oryzae	DNA/RNA Synthesis	Others
Nuclease S1, Aspergillus oryzae is a specific endonuclease that degrades single stranded DNA (ssDNA) and RNA. Nuclease S1 can also remove protruding single-strand ends from double-stranded DNA .

HY-172445

Deoxyribonucleic acid sodium salt from salmon testes SS-DNA	Biochemical Assay Reagents	Others
Deoxyribonucleic acid sodium salt from salmon testes (ssstDNA) can be used to make anti-adhesion layers (AALs) for passivating gold plasmonic sensor surfaces .

HY-R04608

*RAD51 SSDNA-1*	MicroRNA	Cancer
RAD51 SSDNA-1 is a chemically synthesized miRNA mimic that mimics endogenous miRNAs and upregulates miRNA activity for gain-of-function studies .

RAD51 SSDNA-1 RAD51 SSDNA-1

HY-160258

GDP-Fucose-Tz GDP-Fucose-Am-Tz	Biochemical Assay Reagents	Others
GDP-Fucose-Tz (GDP-Fucose-Am-Tz) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. GDP-fucose-Am-Tz and TCO-ssDNA were reacted at a ratio of 1:1 to obtain the final product GDP-fucose-ssDNA .

HY-150626

SARS-CoV-2 nsp13-IN-5	SARS-CoV	Infection
SARS-CoV-2 nsp13-IN-5 (compound C6) is a potent SARS-CoV-2 nsp13 inhibitor with IC₅₀ values of 50 and 55 μM for ssDNA ⁺ ATPase and ssDNA ^- ATPase. SARS-CoV-2 nsp13-IN-5 can be used for researching anti-COVID-19 .

HY-150632

SARS-CoV-2 nsp13-IN-6	SARS-CoV	Infection
SARS-CoV-2 nsp13-IN-6 (compound C5) is a potent SARS-CoV-2 non-structural protein 13 (nsp13) inhibitor with IC₅₀ values of 27 and 33 μM for ssDNA ⁺ ATPase and ssDNA ^- ATPase. SARS-CoV-2 nsp13-IN-6 can be used for researching anti-COVID-19 .

HY-150623

SARS-CoV-2 nsp13-IN-2	SARS-CoV	Infection
SARS-CoV-2 nsp13-IN-2 (Compound C2) is a SARS-CoV-2 non-structural protein 13 (nsp13) small-molecule inhibitor with an IC₅₀ of 42 μM against nsp13 ssDNA ⁺ ATPase .

HY-150624

SARS-CoV-2 nsp13-IN-3	SARS-CoV	Infection
SARS-CoV-2 nsp13-IN-3 (Compound C3) is a SARS-CoV-2 non-structural protein 13 (nsp13) small-molecule inhibitor with an IC₅₀ of 32 μM against nsp13 ssDNA ⁺ ATPase .

HY-101879

Acridine Orange hydrochloride Maximum Cited Publications 25 Publications Verification	DNA Stain Parasite Fluorescent Dye	Others
Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .

HY-160049

BC15 aptamer sodium	Nucleoside Antimetabolite/Analog Biochemical Assay Reagents	Cancer
BC15 aptamer sodium is an ssDNA aptamer targeting the intracellular protein hnRNP A1, which is highly expressed in cancerous liver tissue. BC15 aptamer sodium specifically recognizes breast cancer cells and can be used to detect cancer cells in other pathological types of breast cancer tissue .

HY-D0942

Acridine Orange zinc chloride salt Maximum Cited Publications 25 Publications Verification Euchrysine 3RX	Parasite Fluorescent Dye DNA Stain	Others
Acridine Orange (Euchrysine 3RX) zinc chloride salt is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange zinc chloride salt produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .

HY-126972A

RI(dl)-2 TFA 1 Publications Verification	RAD51	Cancer
RI(dl)-2 TFA is a potent and selective RAD51-mediated D-loop formation inhibitor with an IC₅₀ of 11.1 μM. RI(dl)-2 TFA does not influence RAD51 binding to ssDNA and inhibits homologous recombination (HR) activity in human cells (IC₅₀ of 3.0 μM) .

HY-P10680

TFE-IDAtp1-LinA	Liposome	Others
TFE-IDAtp1-LinA is a highly potent amphiphilic carrier, containing a trifluoroethyl-iminodiacetic acid analog of Stp. TFE-IDAtp1-LinA, formed nanoparticles with Cas9 RNP/ssDNA, achieved enhanced green fluorescent protein knockouts with an ED₅₀ of 0.38 nM Cas9/sgRNA ribonucleoproteins (RNP) .

HY-12342

ML216 5+ Cited Publications CID-49852229	DNA/RNA Synthesis	Cancer
ML216 (CID-49852229) is a potent, selective and cell permeable inhibitor of the DNA unwinding activity of BLM helicase with IC₅₀s of 2.98 μM and 0.97 μM for BLM ^full-length and BLM ^636-1298, respectively. ML216 inhibits ssDNA-dependent ATPase activity of BLM with a K_i of 1.76 µM. Antitumor avtivity .

HY-169622

RAD51-IN-9	RAD51	Others
RAD51-IN-9 (Compound 3a) is a RAD51 inhibitor that can inhibit the binding of RAD51 to ssDNA with an IC₅₀ of 17.85 μM. RAD51-IN-9 has a LD₅₀ against HEK293 cells of 40.21 μM. RAD51-IN-9 can sensitize cells to Mitomycin C (HY-13316) .

HY-150625

SARS-CoV-2 nsp13-IN-4	SARS-CoV	Infection
SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective nsp13 helicase small-molecule inhibitor and inhibit the ssDNA+ ATPase activity of nsp13 with an IC₅₀ value of 57 μM. SARS-CoV-2 nsp13-IN-4 is agentlike molecule with molecular weight of less than 450Da and can provide a broad-spectrum antiviral effect .

HY-D0952

Acridine Orange base Maximum Cited Publications 25 Publications Verification	Parasite	Others
Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays .

Cat. No.	Product Name	Type

HY-101879

Acridine Orange hydrochloride Maximum Cited Publications 25 Publications Verification	Fluorescent Dyes/Probes
Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .

HY-D0942

Acridine Orange zinc chloride salt Maximum Cited Publications 25 Publications Verification Euchrysine 3RX	DNA Stain
Acridine Orange (Euchrysine 3RX) zinc chloride salt is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange zinc chloride salt produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .

HY-D0952

Acridine Orange base Maximum Cited Publications 25 Publications Verification	Fluorescent Dyes/Probes
Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays .

Acridine Orange base

Maximum Cited Publications

25 Publications Verification

Fluorescent Dyes/Probes

Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays .

Cat. No.	Product Name	Type

HY-D0942

Acridine Orange zinc chloride salt 20+ Cited Publications Euchrysine 3RX	DNA Stain
Acridine Orange (Euchrysine 3RX) zinc chloride salt is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange zinc chloride salt produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .

HY-172445

Deoxyribonucleic acid sodium salt from salmon testes SS-DNA	Cell Assay Reagents
Deoxyribonucleic acid sodium salt from salmon testes (ssstDNA) can be used to make anti-adhesion layers (AALs) for passivating gold plasmonic sensor surfaces .

Cat. No.	Product Name	Target	Research Area

HY-P10680

TFE-IDAtp1-LinA	Liposome	Others
TFE-IDAtp1-LinA is a highly potent amphiphilic carrier, containing a trifluoroethyl-iminodiacetic acid analog of Stp. TFE-IDAtp1-LinA, formed nanoparticles with Cas9 RNP/ssDNA, achieved enhanced green fluorescent protein knockouts with an ED₅₀ of 0.38 nM Cas9/sgRNA ribonucleoproteins (RNP) .

Cat. No.	Product Name		Classification

HY-160258

GDP-Fucose-Tz GDP-Fucose-Am-Tz		Tetrazine
GDP-Fucose-Tz (GDP-Fucose-Am-Tz) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. GDP-fucose-Am-Tz and TCO-ssDNA were reacted at a ratio of 1:1 to obtain the final product GDP-fucose-ssDNA .

HY-P10680

TFE-IDAtp1-LinA		Azide
TFE-IDAtp1-LinA is a highly potent amphiphilic carrier, containing a trifluoroethyl-iminodiacetic acid analog of Stp. TFE-IDAtp1-LinA, formed nanoparticles with Cas9 RNP/ssDNA, achieved enhanced green fluorescent protein knockouts with an ED₅₀ of 0.38 nM Cas9/sgRNA ribonucleoproteins (RNP) .

Cat. No.	Product Name		Classification

HY-160046

AS2 sodium		Aptamers
AS2 sodium is an ssDNA aptamer (Kd: 0.7 nM) for prostate-specific antigen (PSA). AS2 sodium does not bind non-specifically to the anti-target and has the potential to be used in diagnostic systems for prostate cancer detection .

HY-160049

BC15 aptamer sodium		Aptamers
BC15 aptamer sodium is an ssDNA aptamer targeting the intracellular protein hnRNP A1, which is highly expressed in cancerous liver tissue. BC15 aptamer sodium specifically recognizes breast cancer cells and can be used to detect cancer cells in other pathological types of breast cancer tissue .

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