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SULT2A1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Endogenous Metabolite (1) Keap1-Nrf2 (1) Small Interfering RNA (siRNA) (2)
By Research Areas:	Metabolic Disease (1)
Oligonucleotides:	Pre-designed siRNA Sets (2) siRNAs (2)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

SULT2A1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SULT2A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT2A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SULT2A1 Human Pre-designed siRNA Set A SULT2A1 Human Pre-designed siRNA Set A

4-Hydroxyphenylacetic acid (Standard)	Keap1-Nrf2 Endogenous Metabolite	Metabolic Disease
4-Hydroxyphenylacetic acid (Standard) is the analytical standard of 4-Hydroxyphenylacetic acid. This product is intended for research and analytical applications. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2 . IC₅₀ & Target:Nrf2 In Vivo: 4-Hydroxyphenylacetic acid (6, 12, or 25 mg/kg) increases Nrf2 translocation to the nucleus and enhances the activity of phase II and antioxidant enzymes. The protein levels of nuclear Nrf2 are increased by 170% and 230% in pre-treated 12 and 25 mg/kg 4-Hydroxyphenylacetic acid groups, respectively, compared with the control group.The 4-Hydroxyphenylacetic acid pretreatment at a final dose of 25 mg/kg markedly and selectively up-regulated the target genes of phase II enzymes and resulted in higher up-regulation than that of the control group by 270%, 400%, and 500% or UGT1A1, UGT1A9, and SULT2A1, respectively. 4-Hydroxyphenylacetic acid also suppresses the expression of CYP2E1 .

SULT2B1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SULT2B1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT2B1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SULT2B1 Human Pre-designed siRNA Set A SULT2B1 Human Pre-designed siRNA Set A

Cat. No.	Product Name	Category	Target	Chemical Structure

4-Hydroxyphenylacetic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Monophenols Source classification Phenols Plants Compositae Endogenous metabolite Erythrina latissima E. Mey.	Keap1-Nrf2 Endogenous Metabolite
4-Hydroxyphenylacetic acid (Standard) is the analytical standard of 4-Hydroxyphenylacetic acid. This product is intended for research and analytical applications. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2 . IC₅₀ & Target:Nrf2 In Vivo: 4-Hydroxyphenylacetic acid (6, 12, or 25 mg/kg) increases Nrf2 translocation to the nucleus and enhances the activity of phase II and antioxidant enzymes. The protein levels of nuclear Nrf2 are increased by 170% and 230% in pre-treated 12 and 25 mg/kg 4-Hydroxyphenylacetic acid groups, respectively, compared with the control group.The 4-Hydroxyphenylacetic acid pretreatment at a final dose of 25 mg/kg markedly and selectively up-regulated the target genes of phase II enzymes and resulted in higher up-regulation than that of the control group by 270%, 400%, and 500% or UGT1A1, UGT1A9, and SULT2A1, respectively. 4-Hydroxyphenylacetic acid also suppresses the expression of CYP2E1 .

Cat. No.	Compare	Product Name	Species	Source

	SULT2A1 Protein, Human (His) Bile Salt Sulfotransferase; Dehydroepiandrosterone Sulfotransferase; DHEA-ST; Hydroxysteroid Sulfotransferase; HST; ST2; ST2A3; Sulfotransferase 2A1; ST2A1; SULT2A1; HST; STD	Human	E. coli
	The SULT2A1 protein utilizes PAPS for critical sulfonation of steroids and bile acids in the liver and adrenal glands. Its multifunctional activity extends to a variety of compounds, enhancing its water solubility to facilitate renal excretion. SULT2A1 Protein, Human (His) is the recombinant human-derived SULT2A1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SULT2A1 Protein, Human (His) is 284 a.a., with molecular weight of 34-38 kDa.

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SULT2A1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
SULT2A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT2A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SULT2B1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
SULT2B1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT2B1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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