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Results for "

Schistosoma mansoni

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

1

Fluorescent Dye

1

Peptides

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112205A
    RR-11a analog
    4 Publications Verification

    		 Parasite Legumain Infection
    RR-11a analog is a potent and irreversible inhibitor of Schistosoma mansoni legumain, with an IC50 of 31 nM. RR-11a analog is an aza-Asn derivative and aza-peptide Michael acceptor .
    RR-11a analog
  • HY-120959
    DAUDA

    		Fluorescent Dye Parasite Others
    DAUDA (11-(dansylamino) undecanoic acid) is an environment-sensitive fluorescent fatty acid analogue. DAUDA alters its intensities and fluorescent emission spectra on entry into binding proteins. DAUDA is used to determine the relative affinity of natural fatty acids for polymorphs of the Schistosoma mansoni Sm14 fatty acid-binding protein[1].
    DAUDA
  • HY-134454
    Z-Pro-Pro-CHO

    		Parasite Prolyl Endopeptidase (PREP) Infection
    Z-Pro-Pro-CHO is a prolyl oligopeptidase inhibitor (IC50: 0.16 μM and 0.01 μM for human and Schistosoma Mansoni prolyl oligopeptidase respectively) .
    Z-Pro-Pro-CHO
  • HY-N2381
    Menthone

    		NF-κB Parasite Infection Metabolic Disease Inflammation/Immunology Cancer
    Menthone, an orally active monoterpene that can be isolated from plants and Mentha oil with antibacterial, antitumor, antioxidation, and antivirus properties. Menthone is a main volatile component of the essential oil, and has anti-Inflammatory properties in Schistosoma mansoni infection and rheumatoid arthritis .
    Menthone
  • HY-111028
    J1038

    T 5979345

    		 HDAC Infection
    J1038 (T 5979345) is a selective HDAC8 inhibitor. J1038 binds the catalytic zinc ion of Schistosoma mansoni HDAC8 (smHDAC8) .
    J1038
  • HY-161596
    SmCB1-IN-1

    		Parasite Cathepsin Infection
    SmCB1-IN-1 (Compound 2h) is an inhibitor for S. mansoni cathepsin B1 (SmCB1) with an Ki of 0.05 μM . SmCB1-IN-1 exhibits selectivity toward human off-target cathepsins (29% and 37% inhibition for CatB and CatL at 20 μM). SmCB1-IN-1 inhibits 68% Schistosoma mansoni at 1 μM .
    SmCB1-IN-1
  • HY-144098
    HDAC8-IN-2

    		Parasite HDAC Others
    HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor, with IC50 values of 0.27 and 0.32 μM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. HDAC8-IN-2 shows significant killing of the schistosome larvae. HDAC8-IN-2 markedly impairs egg laying of adult worm pairs .
    HDAC8-IN-2
  • HY-131508
    M&B 5124

    		Parasite Infection
    M&B 5124 is a potent inhibitor of Schistosoma mansoni in mice .
    M&B 5124
  • HY-151433
    Antiparasitic agent-10

    		Parasite Infection
    Antiparasitic agent-10 (Compound 94) is an anti-parasitic agent, shows anti-schistosomal activity. Antiparasitic agent-10 shows activity against adults of Schistosoma mansoni, and can be used in Schistosomiasis research .
    Antiparasitic agent-10
  • HY-119550
    J1075

    		HDAC Parasite Infection
    J1075 is a selective Schistosoma mansoni HDAC8 inhibitor (with decreased affinity for human HDAC8). J1075 can induce apoptosis (Apoptosis) and death in schistosome cells. J1075 holds research value in the field of anti-parasitic agents .
    J1075
  • HY-119586
    LG190119

    		VD/VDR Cancer
    J1075 is a selective Schistosoma mansoni HDAC8 modulator (with decreased affinity for human HDAC8). J1075 can induce apoptosis (Apoptosis) and death in schistosome cells. J1075 holds research value in the field of anti-parasitic agents .
    LG190119
  • HY-N2381R
    Menthone (Standard)

    		NF-κB Parasite Infection Metabolic Disease Inflammation/Immunology Cancer
    Menthone (Standard) is the analytical standard of Menthone. This product is intended for research and analytical applications. Menthone, an orally active monoterpene that can be isolated from plants and Mentha oil with antibacterial, antitumor, antioxidation, and antivirus properties. Menthone is a main volatile component of the essential oil, and has anti-Inflammatory properties in Schistosoma mansoni infection and rheumatoid arthritis .
    Menthone (Standard)

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