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Results for "

Seliciclib

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-30237
    (R)-Roscovitine
    Maximum Cited Publications
    32 Publications Verification

    Seliciclib; CYC202

    		 CDK Cancer
    (R)-Roscovitine (Seliciclib) is an orally bioavailable and selective CDKs inhibitor with IC50s of 0.2 μM, 0.65 μM, and 0.7 μM for CDK5, Cdc2, and CDK2, respectively.
    (R)-Roscovitine
  • HY-157071S
    Seliciclib Carboxylic Acid-d7

    		Isotope-Labeled Compounds Others
    Seliciclib Carboxylic Acid-d7 is deuterium-labeled Seliciclib Carboxylic Acid .
    Seliciclib Carboxylic Acid-d7
  • HY-30237S
    (R)-Roscovitine-d7

    Seliciclib-d7; CYC202-d7

    		 CDK Isotope-Labeled Compounds Cancer
    (R)-Roscovitine-d7 (Seliciclib-d7; CYC202-d7) is deuterium-labeled (R)-Roscovitine (HY-30237) .
    (R)-Roscovitine-d7
  • HY-112403
    (S)-Roscovitine

    (S)-Seliciclib; (S)-CYC202

    		 CDK Neurological Disease
    (S)-Roscovitine ((S)-Seliciclib; (S)-CYC202) is a potent and cross the blood-brain barrier CDKs inhibitor. (S)-Roscovitine shows neuroprotective efficacy. (S)-Roscovitine has the potential for the research of stroke .
    (S)-Roscovitine
  • HY-110368
    BS-181 dihydrochloride

    		CDK Cancer
    BS-181 dihydrochloride is a potent and selective CDK7 inhibitor (IC50=21 nM) than Seliciclib (HY-30237). BS-181 is also against CDK2, CDK5 and CDK9 with IC50 values of 880 nM, 3000 nM and 4200 nM, respectively (fails to block CDK1, 4 and 6). BS-181 dihydrochloride inhibits a panel of cancer cells growth (IC50=11.5 μM-37.3 μM) and induces cell apoptosis. BS-181 dihydrochloride has the potential for the research of cancer therapy .
    BS-181 dihydrochloride
  • HY-13266
    BS-181

    		CDK Apoptosis Cancer
    BS-181 is a potent and selective CDK7 inhibitor (IC50=21 nM) than Seliciclib (HY-30237). BS-181 is also against CDK2, CDK5 and CDK9 with IC50 values of 880, 3000 and 4200 nM, respectively (fails to block CDK1, 4 and 6). BS-181 inhibits a panel of cancer cells growth (IC50=11.5 μM-37.3 μM) and induces cell apoptosis. BS-181 has the potential for the research of cancer therapy .
    BS-181

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