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Sirolimus-<sup>13</sup>C,d<sub>3</sub>

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10219S1
    Rapamycin-13C,d3

    Sirolimus-<sup>13sup>C,d<sub>3sub>; AY-22989-<sup>13sup>C,d<sub>3sub>

    		 Isotope-Labeled Compounds mTOR FKBP Autophagy Cancer
    Rapamycin- 13C,d3 (Sirolimus- 13C,d3; AY-22989- 13C,d3) is the 13C and deuterium labeled Rapamycin (HY-10219) .Rapamycin is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant .
    Rapamycin-13C,d3

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