Search Result

Search Result

Results for "

Subchronic toxicity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aminopeptidase (1) Apoptosis (2) Autophagy (2) Biochemical Assay Reagents (3) Fluorescent Dye (1) Peptide-Drug Conjugate (PDC) (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (2)
Oligonucleotides:	Release-retarding Agents (1)

8

Inhibitors & Agonists

2

Biochemical Assay Reagents

1

Peptides

2

Natural
Products

1

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Dehydrothio-p-toluidine 1 Publications Verification DHPT	Fluorescent Dye	Others
Dehydrothio-p-toluidine (DHPT) is a chemical intermediate used in dyestuff production. Dehydrothio-p-toluidine shows inhalation toxicity in acute and subchronic conditions .

Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da)	Biochemical Assay Reagents	Others
Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) is a cosolvent for preparing SDDs of low-solubility agents. Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) exhibits no acute/subchronic/chronic toxicity in rats, with oral activity and LD₅₀ >2.5 g/kg .

HY-D1005A22

Poloxamer 338 (F108) PEG-PPG-PEG, 14600 (Averag)	Biochemical Assay Reagents	Others
Poloxamer 338 F108 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 14600. Poloxamer 338 F108 reduces the aggregation of red blood cells, inhibits proliferation of human lymphocyte cell IIBR1. Poloxamer 338 F108 exhibits short-term and subchronic toxicity in rats .

Dioscin 5+ Cited Publications Collettiside III; CCRIS 4123	Autophagy Apoptosis	Cardiovascular Disease Cancer
Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity .

AD-20	Others	Cancer
AD-20 is an o-methoxyphenylacetyl dehydroalanine derivative. AD-20 can not only reduce the acute and subchronic toxicity of Doxorubicin (HY-15142A), but also enhance its anti-tumor effect .

HY-D1005A16

Poloxamer 235 (P85) PEG-PPG-PEG, 4600 (Averag)	Biochemical Assay Reagents	Others
Poloxamer 235 P85 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 4600. Poloxamer 235 P85 exhibits acute and subchronic toxicity in albino rats with an oral LD₅₀ of >34.6 g/kg. Poloxamer 235 P85 induces ocular irritation in rabbits .

DTS-201 sodium	Peptide-Drug Conjugate (PDC) Aminopeptidase	Cancer
DTS-201 sodium (CPI-0004Na) is a peptidic prodrug of Doxorubicin (HY-15142A). DTS-201, comprising the tetrapeptide portion, is cleaved by endopeptidases in the tumor environment to produce metabolites that subsequently enter the cell and are converted to active Doxorubicin. DTS-201 shows antitumoral efficacy in tumor xenograft models of prostate, breast, and lung cancer .

Dioscin (Standard)	Autophagy Apoptosis	Cardiovascular Disease Cancer
Dioscin (Standard) is the analytical standard of Dioscin. This product is intended for research and analytical applications. Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity .

Cat. No.	Product Name	Type

HY-D1005A22

Poloxamer 338 (F108) PEG-PPG-PEG, 14600 (Averag)	Co-solvents
Poloxamer 338 F108 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 14600. Poloxamer 338 F108 reduces the aggregation of red blood cells, inhibits proliferation of human lymphocyte cell IIBR1. Poloxamer 338 F108 exhibits short-term and subchronic toxicity in rats .

HY-D1005A16

Poloxamer 235 (P85) PEG-PPG-PEG, 4600 (Averag)	Co-solvents
Poloxamer 235 P85 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 4600. Poloxamer 235 P85 exhibits acute and subchronic toxicity in albino rats with an oral LD₅₀ of >34.6 g/kg. Poloxamer 235 P85 induces ocular irritation in rabbits .

Cat. No.	Product Name	Target	Research Area

DTS-201 sodium	Peptide-Drug Conjugate (PDC) Aminopeptidase	Cancer
DTS-201 sodium (CPI-0004Na) is a peptidic prodrug of Doxorubicin (HY-15142A). DTS-201, comprising the tetrapeptide portion, is cleaved by endopeptidases in the tumor environment to produce metabolites that subsequently enter the cell and are converted to active Doxorubicin. DTS-201 shows antitumoral efficacy in tumor xenograft models of prostate, breast, and lung cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure

Dioscin 5+ Cited Publications Collettiside III; CCRIS 4123	Structural Classification other families Classification of Application Fields Source classification Plants Disease Research Fields Steroids Cancer	Autophagy Apoptosis
Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity .

Dioscin (Standard)	Structural Classification other families Source classification Plants Steroids	Autophagy Apoptosis
Dioscin (Standard) is the analytical standard of Dioscin. This product is intended for research and analytical applications. Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity .

Cat. No.	Product Name		Classification

Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da)		Release-retarding Agents
Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) is a cosolvent for preparing SDDs of low-solubility agents. Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) exhibits no acute/subchronic/chronic toxicity in rats, with oral activity and LD₅₀ >2.5 g/kg .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

MedChemExpress Magic Cece

MedChemExpress: Contact Us; About Us; Headquarters; Distributors; Statement on False Report; Careers

Customer Support: Technical Support; Service; Ordering Information; Easy Return; Shipping Rates & Policies; Intellectual Property Promise

Resources: Free Sample; Resources; Molarity Calculator; Dilution Calculator; Terms & Conditions; Reconstitution Calculator; Specific Activity Calculator

Subscribe to our E-newsletter

Name
Email *

	Sorry, but the email address you supplied was invalid.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.

Copyright © 2013-2025 MedChemExpress. All Rights Reserved.: Site Map Privacy Policy

Join with us