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Syringaresinol

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AP-1 (1) Bacterial (1) Drug Isomer (1) NF-κB (2) NO Synthase (2) Nuclear Factor of activated T Cells (NFAT) (1) p38 MAPK (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (2) Metabolic Disease (2)

9

Inhibitors & Agonists

9

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

(-)-Syringaresinol	Drug Isomer NO Synthase NF-κB	Cancer
(-)-Syringaresinol, is the isoform of Syringaresinol (HY-N8307), which can be found in stems of Annona Montana, possesses anti-cancer activity. Syringaresinol is an activator of NO synthase phosphorylation and induces vasodilation. Syringaresinol also inhibits the NF-κB pathway and exerts anti-inflammatory activity .

*Syringaresinol*	NO Synthase NF-κB	Cardiovascular Disease Inflammation/Immunology
Syringaresinol is a lignan that can be extracted from the dragon's blood of the Dracaena tree. Syringaresinol increases NO production by increasing the phosphorylation and dimerization of endothelial NO synthase, exerting a vasodilatory effect. Syringaresinol also inhibits the NF-κB pathway, exerting anti-inflammatory activity and inhibiting arthritis .

Syringaresinol diglucoside Syringaresinol-di-O-glucoside	Others	Metabolic Disease
Syringaresinol diglucoside is a natural compound from bamboo leaves .

(+)-Syringaresinol	Nuclear Factor of activated T Cells (NFAT)	Cancer
(+)-Syringaresinol, a lignan, is a NFAT transcription factor inhibitor, with an IC₅₀ of 329.4 μM. (+)-Syringaresinol also can be used for the research of lymphocytic leukemia .

*DL-Syringaresinol* diacetate** Syringaresinol Diacetate	Others	Cancer
DL-Syringaresinol diacetate is a glucoside. DL-Syringaresinol inhibits cAMP phosphodiesterase and alleviation of stress .

Syringaresinol diglucoside (Standard)	Others	Metabolic Disease
Syringaresinol diglucoside (Standard) is the analytical standard of Syringaresinol diglucoside. This product is intended for research and analytical applications. Syringaresinol diglucoside is a natural compound from bamboo leaves .

Diayangambin Syringaresinol dimethyl ether; Lirioresinol C dimethyl ether	Others	Inflammation/Immunology
Diayangambin (Syringaresinol dimethyl ether; Lirioresinol C dimethyl ether) is a cell proliferation inhibitor with an IC₅₀ value of 1.5 μM against human monocytes. Diayangambin also has immunosuppressive and anti-inflammatory effects .

DL-Syringaresinol (±)-Syringaresinol	p38 MAPK AP-1 Bacterial	Infection
DL-Syringaresinol ((±)-Syringaresinol), a lignin, inhibits UVA-induced upregulation of MMP-1 by suppressing MAPK/AP-1 signaling in human HaCaT keratinocytes and dermal fibroblasts (HDFs). DL-Syringaresinol has antiphotoaging properties against UVA-induced skin aging. DL-Syringaresinol exhibits weak antimycobacterial activity against Mycobacterium tuberculosis H37Rv .

epi-Syringaresinol	Others	Others
epi-Syringaresinol is a phenolic compound isolated from Sapium discolor .

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