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Results for "

TACC3

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

1

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145895
    SNIPER(TACC3)-11

    		FGFR SNIPERs Cancer
    SNIPER(TACC3)-11 is a potent FGFR3-TACC3 degrader. SNIPER(TACC3)-11 reduces FGFR3-TACC3 protein levels and suppressed the growth of FGFR3-TACC3 positive cancer cells .
    SNIPER(TACC3)-11
  • HY-111876
    SNIPER(TACC3)-1

    		SNIPERs Cancer
    SNIPER(TACC3)-1 targets the TACC3 protein for degradation via the ubiquitin-proteasome pathway based on IAP ligand. SNIPER(TACC3)-1 induces cancer cell death .
    SNIPER(TACC3)-1
  • HY-111877
    SNIPER(TACC3)-2

    		SNIPERs Cancer
    SNIPER(TACC3)-2 targets the TACC3 protein for degradation via the ubiquitin-proteasome pathway based on IAP ligand. SNIPER(TACC3)-2 induces cancer cell death .
    SNIPER(TACC3)-2
  • HY-135960
    BO-264

    		FGFR Apoptosis Cancer
    BO-264 is a highly potent and orally active transforming acidic coiled-coil 3 (TACC3) inhibitor with an IC50 of 188 nM and a Kd of 1.5 nM. BO-264 specifically blocks the function of FGFR3-TACC3 fusion protein. BO-264 induces spindle assembly checkpoint (SAC)-dependent mitotic arrest, DNA damage and apoptosis. BO-264 has broad-spectrum antitumor activity .
    BO-264
  • HY-120087
    KG-548

    		HIF/HIF Prolyl-Hydroxylase Cancer
    KG-548 is an ARNT/TACC3 disruptor and a HIF-1α inhibitor. KG-548 directly interferes with ARNT/TACC3 complex formation by competing with TACC3 for binding to the ARNT PAS-B domain. ARNT is the aryl hydrocarbon receptor nuclear translocator, also known as HIF-β .
    KG-548
  • HY-151985
    TACC3 inhibitor 1

    		Apoptosis Cancer
    TACC3 inhibitor 1 is a potent and cross the blood-brain barrier TACC3 inhibitor. TACC3 inhibitor 1 induces Apoptosis and cell cycle arrest at G2/M phase. TACC3 inhibitor 1 induces the generation of intracellular ROS. TACC3 inhibitor 1 shows antiproliferative and anti-tumor activity .
    TACC3 inhibitor 1
  • HY-170960
    TACC3 inhibitor 2

    		Microtubule/Tubulin Cancer
    TACC3 inhibitor 2 (Compound 13b) is a TACC3 inhibitor with an IC50 of 200 nM. TACC3 inhibitor 2 can induce mitotic arrest, cell apoptosis (Apoptosis), and DNA damage. TACC3 inhibitor 2 can be used for cancer research .
    TACC3 inhibitor 2
  • HY-RS14141
    TACC3 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    TACC3 Human Pre-designed siRNA Set A contains three designed siRNAs for TACC3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TACC3 Human Pre-designed siRNA Set A
    TACC3 Human Pre-designed siRNA Set A
  • HY-111877A
    SNIPER(TACC3)-2 hydrochloride

    		SNIPERs Cancer
    SNIPER(TACC3)-2 hydrochloride targets the TACC3 protein for degradation via the ubiquitin-proteasome pathway based on IAP ligand. SNIPER(TACC3)-2 hydrochloride induces cancer cell death .
    SNIPER(TACC3)-2 hydrochloride
  • HY-111876A
    SNIPER(TACC3)-1 hydrochloride

    		SNIPERs Cancer
    SNIPERTACC3-1 hydrochloride targets the TACC3 protein for degradation via the ubiquitin-proteasome pathway based on IAP ligand. SNIPERTACC3-1 hydrochloride induces cancer cell death .
    SNIPER(TACC3)-1 hydrochloride
  • HY-10996A
    KHS101 hydrochloride

    		FGFR Neurological Disease Cancer
    KHS101 hydrochloride could selectively induce a neuronal differentiation phenotype and interacts with transforming acidic coiled-coil-containing protein 3 (TACC3).
    KHS101 hydrochloride
  • HY-W012248
    KG-655

    		Aryl Hydrocarbon Receptor Others
    KG-655 is a small molecule compound that binds to the β-folded surface and internal cavity of ARNT PAS-B and interferes with its binding to the transcriptional coactivator TACC3. KG-655 can promote the homodimerization of ARNT PAS-B and has the potential to regulate multiple ARNT-mediated signaling pathways .
    KG-655
  • HY-10996
    KHS101

    		FGFR Neurological Disease
    KHS101 is a small molecule that accelerates neuronal differentiation. KHS101 can distributes to the brain and resulted in a significant increase in neuronal differentiation .
    KHS101

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