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TEM-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (5) Bacterial (6) Beta-lactamase (5)
By Research Areas:	Cancer (1) Infection (7)

7

Inhibitors & Agonists

1

Inhibitory Antibodies

1

Natural
Products

5

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Avibactam sodium Maximum Cited Publications 62 Publications Verification NXL-104	Beta-lactamase Bacterial Antibiotic	Infection
Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase *TEM-1* and CTX-M-15 with IC₅₀s of 8 nM and 5 nM, respectively ^[1].

Avibactam sodium hydrate Maximum Cited Publications 62 Publications Verification NXL-104 hydrate	Beta-lactamase Bacterial Antibiotic	Infection
Avibactam sodium (NXL-104) hydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase *TEM-1* and CTX-M-15 with IC₅₀s of 8 nM and 5 nM, respectively ^[1].

Avibactam free acid Maximum Cited Publications 62 Publications Verification NXL-104 free acid	Beta-lactamase Bacterial Antibiotic	Infection
Avibactam (NXL-104) free acid is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase *TEM-1* and CTX-M-15 with IC₅₀s of 8 nM and 5 nM, respectively ^[1].

Cymal-6 Cyclohexyl-hexyl-β-D-maltoside	Bacterial	Infection
Cymal-6 (Cyclohexyl-hexyl-β-D-maltoside) is a potent TEM-1 beta-lactamase inhibitor with an K_i value of 40.05 µM. Cymal-6 (Cyclohexyl-hexyl-β-D-maltoside) can be used as glycosidic surfactant ^[1] .

Avibactam sodium dihydrate NXL-104 dihydrate	Beta-lactamase Bacterial Antibiotic	Infection
Avibactam sodium (NXL-104) dihydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase *TEM-1* and CTX-M-15 with IC₅₀s of 8 nM and 5 nM, respectively ^[1].

Avibactam sodium (Standard)	Beta-lactamase Bacterial Antibiotic	Infection
Avibactam (sodium) (Standard) is the analytical standard of Avibactam (sodium). This product is intended for research and analytical applications. Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase *TEM-1* and CTX-M-15 with IC₅₀s of 8 nM and 5 nM, respectively ^[1].

ent-Avibactam sodium AVE1330A	Others	Infection
ent-Avibactam sodium (AVE1330A) is a new β-lactamase inhibitor with broad-spectrum antibacterial activity. ent-Avibactam sodium, in combination with ceftazidime, exhibits significant inhibitory effects on Enterobacteriaceae that produce Ambler class A and class C beta-lactamases. The IC₅₀ value of ent-Avibactam sodium is much lower than the commonly used β-lactamase inhibitors clavulanic acid and ticarbonitrile, showing its ability to inhibit TEM-1 and P99 enzyme efficiency ^[1].

Cat. No.	Product Name	Target	Research Area

Ontuxizumab MORAb-004	Inhibitory Antibodies	Cancer
Ontuxizumab (MORAb-004) is a humanized IgG1/κ anti-endosialin (TEM-1 or CD248) monoclonal antibody with antitumor effects. Ontuxizumab can be used for the research of cancer ^[1].

Species:	Human (1) Mouse (1) E.coli (1) Canine (2)
Tag:	His (5)
Source:	HEK293 (4) P. pastoris (1)

Cat. No.	Compare	Product Name	Species	Source

	*Beta-lactamase TEM/Bla Protein, E.coli (P.pastoris, His)* bla; blaT-3; blaT-4; blaT-5; TEM-1; TEM-16/CAZ-7; TEM-2; TEM-24/CAZ-6; TEM-3; TEM-4; TEM-5; TEM-6; TEM-8/CAZ-2	E.coli	P. pastoris
	The β-lactamase TEM/Bla proteome is dominant in Enterobacteriaceae and hydrolyzes β-lactam bonds in β-lactam antibiotics, thereby conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4 hydrolyze cefotaxime and ceftazidime, TEM-5 targets ceftazidime, and TEM-6 includes aztreonam. Beta-lactamase TEM/Bla Protein, E.coli (P.pastoris, His) is the recombinant E. coli-derived Beta-lactamase TEM/Bla protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of Beta-lactamase TEM/Bla Protein, E.coli (P.pastoris, His) is 263 a.a., with molecular weight of ~30.9 kDa.

	Endosialin/CD248 Protein, Human (HEK293, His) Endosialin; CD248; CD164L1; TEM1; CD164 sialomucin-like 1; CD164L1; CD248 molecule; MGC119479	Human	HEK293
	Endosialin/CD248 Protein may contribute to tumor angiogenesis. Endosialin/CD248 Protein, Human (HEK293, His) is the recombinant human-derived Endosialin/CD248 protein, expressed by HEK293 , with C-His labeled tag. The total length of Endosialin/CD248 Protein, Human (HEK293, His) is 670 a.a., with molecular weight of 115-140 kDa.

	Endosialin/CD248 Protein, Mouse (HEK293, His) Endosialin; CD248; CD164L1; TEM1; CD164 sialomucin-like 1; CD164L1; CD248 molecule; MGC119479	Mouse	HEK293
	Endosialin/CD248 Protein potentially plays a role in angiogenesis or vascular function, suggesting involvement in blood vessel formation or vascular regulation. The exact mechanisms and contexts of Endosialin/CD248 in these processes are areas of interest, emphasizing its potential significance in vascular development and function. Endosialin/CD248 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Endosialin/CD248 protein, expressed by HEK293 , with C-His labeled tag. The total length of Endosialin/CD248 Protein, Mouse (HEK293, His) is 678 a.a., with molecular weight of 95-155 kDa.

	TEM1/cd248 Protein, Canine (HEK293, His)	Canine	HEK293

	Endosialin/CD248 Protein, Canine (HEK293, His) Endosialin; CD248; CD164L1; TEM1; CD164 sialomucin-like 1; CD164L1; CD248 molecule	Canine	HEK293
	Endosialin/CD248 Protein potentially plays a role in angiogenesis or vascular function, suggesting involvement in blood vessel formation or vascular regulation. The exact mechanisms and contexts of Endosialin/CD248 in these processes are areas of interest, emphasizing its potential significance in vascular development and function. Endosialin/CD248 Protein, Canine (HEK293, His) is the recombinant canine-derived Endosialin/CD248 protein, expressed by HEK293 , with C-His labeled tag. The total length of Endosialin/CD248 Protein, Canine (HEK293, His) is 670 a.a., with molecular weight of 120-140 kDa.

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