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Results for "

U2AF65

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Natural
Products

2

Recombinant Proteins

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-139104
    Thailanstatin D

    		DNA/RNA Synthesis Apoptosis Cancer
    Thailanstatin D, an analogue of Thailanstatin A, is able to inhibit AR-V7 gene splicing by interfering the interaction between U2AF65 and SAP155 and preventing them from binding to polypyrimidine tract located between the branch point and the 3' splice site. Thailanstatin D exhibits a potent tumor inhibitory effect on human CRPC xenografts leading to cell apoptosis .
    Thailanstatin D
  • HY-148384
    UHMCP1

    		Others Cancer
    UHMCP1 is a chemical probe of U2AF homology motifs (UHM) with a Kd of 79 μM. UHMCP1 prevents the SF3b155/U2AF65 interaction, impacts RNA splicing and cell viability. UHMCP1 has potential anticancer properties .
    UHMCP1
  • HY-148384A
    UHMCP1 dihydrochloride

    		Others Cancer
    UHMCP1 dihydrochloride is a potent UHM domain splicing inhibitor with a Kd value of 79 µM. UHMCP1 dihydrochloride prevents the SF3b155/U2AF 65 interaction. UHMCP1 dihydrochloride impacts cell viability and RNA splicing .
    UHMCP1 dihydrochloride

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