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Results for "

USP5

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

2

Recombinant Proteins

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-139979
    USP5-IN-1
    1 Publications Verification

    		 Deubiquitinase Cancer
    USP5-IN-1 (compound 64), a potent deubiquitinase USP5 inhibitor, binds to the USP5 ZnF-UBD with a KD of 2.8 μM. USP5-IN-1 is selective over nine proteins containing structurally similar ZnF-UBD domains. USP5-IN-1 inhibits the USP5 catalytic cleavage of a di-ubiquitin substrate .
    USP5-IN-1
  • HY-103435
    Vialinin A
    2 Publications Verification

    Terrestrin A

    		 Deubiquitinase Inflammation/Immunology Cancer
    Vialinin A (Terrestrin A) is a p-terphenyl compound with antioxidant properties . Vialinin A is a potent inhibitor of TNF-α, USP4, USP5, and sentrin/SUMO-specific protease 1 (SENP1). Vialinin A (Terrestrin A) can be used for autoimmune diseases and cancer research .
    Vialinin A
  • HY-111408
    EOAI3402143
    5+ Cited Publications

    		 Deubiquitinase Cancer
    EOAI3402143 is a deubiquitinase (DUB) inhibitor, which inhibits dose-dependently inhibits Usp9x/Usp24 and Usp5.
    EOAI3402143
  • HY-13264
    Degrasyn
    10+ Cited Publications

    WP1130

    		 Deubiquitinase Bcr-Abl Autophagy Apoptosis Cancer
    Degrasyn (WP1130) is a cell-permeable deubiquitinase (DUB) inhibitor, directly inhibiting DUB activity of USP9x, USP5, USP14, and UCH37. Degrasyn has been shown to downregulate the antiapoptotic proteins Bcr-Abl and JAK2.
    Degrasyn
  • HY-122243
    IU1-47
    2 Publications Verification

    		 Deubiquitinase Neurological Disease
    IU1-47 is a potent and specific USP14 inhibitor with an IC50 of 0.6 μM. IU1-47 inhibits IsoT/USP5 with an IC50 of 20 μM. IU1-47 induces tau elimination in cultured neurons .
    IU1-47
  • HY-13814
    PR-619
    Maximum Cited Publications
    17 Publications Verification

    		 Deubiquitinase Autophagy Apoptosis Cancer
    PR-619 is a broad-range and reversible DUB inhibitor with EC50s of 3.93, 4.9, 6.86, 7.2, and 8.61 μM for USP4, USP8, USP7, USP2, and USP5, respectively. PR-619 induces ER Stress and ER-Stress related apoptosis .
    PR-619
  • HY-134817
    USP7-IN-8
    1 Publications Verification

    		 Deubiquitinase Cancer
    USP7-IN-8 (example 81) is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM in an Ub-Rho110 assay. USP7-IN-8 shows no activity against USP47 and USP5. USP7-IN-8 has anticancer effects .
    USP7-IN-8
  • HY-RS15561
    USP5 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    USP5 Human Pre-designed siRNA Set A contains three designed siRNAs for USP5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    USP5 Human Pre-designed siRNA Set A
    USP5 Human Pre-designed siRNA Set A

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