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UU

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-117233
    UU-T02
    1 Publications Verification

    		 β-catenin Wnt Metabolic Disease Cancer
    UU-T02 is a novel potent, selective small-molecule inhibitor of β-Catenin/T-cell factor protein-protein interaction (β-catenin/Tcf PPI) with a Ki of 1.36 μM . UU-T02 inhibits canonical Wnt signaling and the growth of colorectal cancer cells .
    UU-T02
  • HY-159806
    UU

    (3′,5′)-Uridylyluridine

    		 Nucleoside Antimetabolite/Analog Metabolic Disease
    UU ((3′,5′)-Uridylyluridine) is a nucleobase-containing dinucleotide derivative. UU can be used for the study of RNA-related processes .
    UU
  • HY-122649
    UU-T01

    		β-catenin Cancer
    UU-T01 is a selective inhibitor for β-Catenin/T-cell factor 4 protein-protein interaction (β-catenin/Tcf PPI) with an Ki value of 3.14 µM. UU-T01 is directly combined with β-catenin, and the KD value is 0.531 µM .
    UU-T01
  • HY-160939
    ASK1-IN-6

    		MAP3K Neurological Disease Inflammation/Immunology
    ASK1-IN-6 (Compound 32) is a selective inhibitor for apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 25 nM. ASK1-IN-6 is blood brain barrier penetrate(rat Cl/Clu is 1.6/56 L/h/kg and Kp,uu is 0.46). ASK1-IN-6 exhibits anti-inflammatory avtivity and ameliorates the Alzheimer’s Disease in Tg4510 mouse model .
    ASK1-IN-6

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