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Isoforms Recommended: V1b Receptor 
Results for "

V1B receptor

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

6

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-117820
    TASP0390325

    		Vasopressin Receptor Cardiovascular Disease Neurological Disease
    TASP0390325 is a high affinity and orally active arginine vasopressin receptor 1B (V1B receptor) antagonist with antidepressant and anxiolytic activities .
    TASP0390325
  • HY-P1390
    d[Cha4]-AVP

    		Vasopressin Receptor Endocrinology
    d[Cha4]-AVP is a potent and selective vasopressin (AVP) V1b receptor agonist with a Ki of 1.2 nM for human V1b receptor. d[Cha4]-AVP shows more selective for V1b receptor than human V1a receptor, V2 receptor, and oxytocin receptors .
    d[Cha4]-AVP
  • HY-10066
    Nelivaptan

    SSR-149415

    		 Vasopressin Receptor Cardiovascular Disease Neurological Disease
    Nelivaptan (SSR-149415) is a selective and orally active vasopressin V1b Receptor antagonist (Ki: 3.7 and 1.3 nM for native and recombinant rat V1b receptors, respectively). Nelivaptan inhibits arginine vasopressin (AVP)-induced Ca 2+ increase and corticotropin secretion. Nelivaptan can be used for research of stress and anxiety .
    Nelivaptan
  • HY-P1163A
    D[LEU4,LYS8]-VP TFA

    		Vasopressin Receptor Cardiovascular Disease Neurological Disease
    D[LEU4,LYS8]-VP TFA is a selective agonist of vasopressin V1b receptor, with the Kis of 0.16 nM, 0.52 nM, and 0.1.38 nM for rat, human and mouse V1b receptor, respectively. D[LEU4,LYS8]-VP TFA has weak antidiuretic, vasopressor, and in vitro oxytocic activities .
    D[LEU4,LYS8]-VP TFA
  • HY-105685
    SRX246

    		Vasopressin Receptor Cardiovascular Disease Neurological Disease
    SRX246 is a potent, CNS-penetrant, highly selective, orally bioavailable vasopressin 1a (V1a) receptor antagonist (Ki=0.3 nM for human V1a). SRX246 has no interaction at V1b and V2 receptors. SRX246 also displays negligible binding at 64 others receptors classes, including 35 G-proteincoupled receptors. SRX246 can be used for treatment of stress-related disorders .
    SRX246
  • HY-P1390A
    d[Cha4]-AVP TFA

    		Vasopressin Receptor Endocrinology
    d[Cha4]-AVP TFA is a potent and selective vasopressin (AVP) V1b receptor agonist with a Ki of 1.2 nM for human V1b receptor. d[Cha4]-AVP TFA shows more selective for V1b receptor than human V1a receptor, V2 receptor, and oxytocin receptors .
    d[Cha4]-AVP TFA
  • HY-P1163
    D[LEU4,LYS8]-VP

    		Vasopressin Receptor Cardiovascular Disease Neurological Disease
    D[LEU4,LYS8]-VP is a selective agonist of vasopressin V1b receptor, with the Kis of 0.16 nM, 0.52 nM, and 0.1.38 nM for rat, human and mouse V1b receptor, respectively. D[LEU4,LYS8]-VP has weak antidiuretic, vasopressor, and in vitro oxytocic activities .
    D[LEU4,LYS8]-VP
  • HY-118918
    YM218 free base

    		Vasopressin Receptor Endocrinology
    YM218 free base is an orally active non-peptide vasopressin (AVP) receptor antagonist. YM218 free base has a high affinity for rat liver V1A receptors with a Ki value of 0.50 nM; it has a lower affinity for rat pituitary V1B, kidney V2, and uterine oxytocin receptors with Ki values of 1510 nM, 72.2 nM, and 150 nM, respectively. YM218 free base can be used in the study of diabetes and kidney disease .
    YM218 free base
  • HY-P0049A
    Argipressin diacetate

    Arg8-vasopressin diacetate; AVP diacetate; ADH

    		 Apoptosis Vasopressin Receptor Neurological Disease Cancer
    Argipressin (diacetate) (AVP (diacetate), also known as antidiuretic hormone (ADH)) is a 9 amino acid neuropeptide secreted by the posterior pituitary. Argipressin (diacetate) (AVP (diacetate)) can regulate the biological effects of fluid balance, osmolality and cardiovascular through three separate G-protein coupled receptors (GPCRs), namely Avpr1a (V1a), Avpr1b (V1b) and Avpr2 (V2). Argipressin (diacetate) (AVP (diacetate)) also have potentially important effects on centrally regulated metabolic processes .
    Argipressin diacetate

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